Cilostazol and Nimodipine Combined Therapy After Aneurysmal Subarachnoid Hemorrhage (aSAH)

What was said, and by whom

Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.

Also happening at the time. Not shown to be a cause.

Registry events on other trials of drugs against PDE3A within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.

• 2025-05-31Also stopped (withdrawn): Cedars-Sinai Medical Center, Pentoxifylline Oral Product + Placebo (NCT04391231)
• 2025-05-22Also stopped (terminated): Prokrea BCN, S.L., Vaginal product (NCT06986031)
• 2025-05-14Also stopped (suspended): Sclnow Biotechnology Co., Ltd., Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#) + conventional treatment (NCT03180450)
• 2025-05-11Results posted on the registry: Peng Roc Chen, MD, Nicardipine + Verapamil (NCT01996436)
• 2025-05-11Also stopped (terminated): Peng Roc Chen, MD, Nicardipine + Verapamil (NCT01996436)
• 2025-05-09Also stopped (terminated): Medical University of Bialystok, Levosimendan (NCT04705337)
• 2025-04-18Results posted on the registry: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA, Ensifentrine 3 mg twice daily (NCT06460493)
• 2024-11-27Results posted on the registry: University of California, Los Angeles, Ibudilast + Placebo oral capsule (NCT03594435)
• 2024-11-12Phase 3 first posted: Ain Shams University, Melatonin (NCT06685679)
• 2024-11-08Phase 3 first posted: NICHD Neonatal Research Network, Milrinone infusion + Placebo infusion (NCT06679855)
• 2024-10-30Results posted on the registry: MediciNova, Ibudilast + Placebo (NCT04429555)
• 2024-10-23Also stopped (terminated): Niguarda Hospital, Early intra-aortic balloon pump (IABP) implantation (NCT04369573)
• 2024-10-15Results posted on the registry: University of Missouri-Columbia, Pentoxifylline + Placebo (NCT02592863)
• 2024-10-15Also stopped (terminated): University of Missouri-Columbia, Pentoxifylline + Placebo (NCT02592863)
• 2024-10-01Results posted on the registry: Philips Clinical & Medical Affairs Global, a drug against PDE3A (NCT04696354)
• 2024-09-25Also stopped (terminated): Iain Bressendorff, ACEi / ARB, SGLT2i, finerenone, semaglutide, pentoxifylline, hydrochlorthiazide, baricitinib (NCT05897372)
• 2024-09-24Results posted on the registry: MediciNova, ibudilast + Ibudilast (NCT02714036)
• 2024-06-27Phase 3 first posted: Ain Shams University, levosemindan (NCT06478667)
• 2024-06-14Phase 3 first posted: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA, Ensifentrine 3 mg twice daily (NCT06460493)
• 2024-05-20Phase 3 first posted: Ain Shams University, Dapagliflozin 10mg Tab + Pentoxifylline 400 MG (NCT06421870)
• 2024-05-20Phase 3 first posted: Tanta University, Pentoxifylline + Probiotic Formula (NCT06422000)
• 2024-05-14Results posted on the registry: Tenax Therapeutics, Inc., Levosimendan + Matching Placebo (NCT03541603)
• 2024-03-26Results posted on the registry: Göteborg University, Levosimendan + Milrinone (NCT02232399)
• 2024-03-08Phase 3 first posted: Damascus University, The topical application of a vasodilator on the LIMA graft (NCT06301880)
• 2024-01-11Also stopped (terminated): Baylor College of Medicine, Pentoxifylline (NCT01774487)

What is not public

• Internal portfolio and board discussions
• Unpublished trial data and interim analyses
• Terms of any partner or licence decision