Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:43 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Intratumoral Tilsotolimod, a TLR-9 Agonist, Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced Cancers
NCT04270864 · Gustave Roussy, Cancer Campus, Grand Paris · PHASE1 · terminated · last registry update 2024-10-18 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The part A of the trial has been completed according to the protocol. The part B has not been opened because of unfeasibility (experimental products not yet available).” | – | Registry record, Gustave Roussy, Cancer Campus, Grand Paris |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CTLA4 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-10-03Results posted on the registry: Bristol-Myers Squibb, BMS-986408 + Nivolumab (NCT05407675)
- 2025-09-23Results posted on the registry: National Cancer Institute (NCI), Ipilimumab + Nivolumab (NCT02408861)
- 2025-09-22Results posted on the registry: Bristol-Myers Squibb, Ipilimumab + Oxaliplatin (NCT04008030)
- 2025-09-18Results posted on the registry: Bristol-Myers Squibb, Nivolumab + Ipilimumab (NCT03036098)
- 2025-09-10Results posted on the registry: Exelixis, Cabozantinib + Nivolumab (NCT03937219)
- 2025-09-10Phase 3 first posted: NRG Oncology, Atezolizumab + Bevacizumab (NCT07166406)
- 2025-07-25Results posted on the registry: Hackensack Meridian Health, Ipilimumab + Nivolumab (NCT02681302)
- 2025-06-19Results posted on the registry: Bristol-Myers Squibb, BMS-986253 + Nivolumab (NCT03400332)
- 2025-06-16Phase 3 first posted: Akeso, Cadonilimab + SOX chemotherapy (NCT07023315)
- 2025-04-22Results posted on the registry: Emory University, Nivolumab + Rituximab and Hyaluronidase Human (NCT03719131)
- 2025-04-03Results posted on the registry: Dana-Farber Cancer Institute, Nivolumab + Ipilimumab (NCT04938232)
- 2025-03-25Results posted on the registry: H. Lee Moffitt Cancer Center and Research Institute, Nivolumab + Ipilimumab (NCT03377023)
- 2025-03-11Results posted on the registry: Greg Durm, MD, Nivolumab + Nivolumab (NCT03285321)
- 2025-03-05Results posted on the registry: M.D. Anderson Cancer Center, Carboplatin + Cisplatin (NCT03158129)
- 2025-02-21Phase 3 first posted: Gustave Roussy, Cancer Campus, Grand Paris, SoC-based immunotherapy (+/- chemotherapy) (NCT06840782)
- 2025-01-30Results posted on the registry: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Tadalafil + Pembrolizumab (NCT05014776)
- 2025-01-27Phase 3 first posted: Hildur Helgadottir, Nivolumab + Nivolumab + Ipilimumab (NCT06794775)
- 2025-01-07Results posted on the registry: National Cancer Institute (NCI), Decitabine + Ipilimumab (NCT02890329)
- 2024-12-19Phase 3 first posted: Immatics US, Inc., IMA203 + nivolumab plus relatlimab (NCT06743126)
- 2024-12-19Results posted on the registry: Ipsen, Cabozantinib (NCT03945773)
- 2024-11-27Results posted on the registry: Georgetown University, Nivolumab + Ipilimumab (NCT04091750)
- 2024-11-12Results posted on the registry: Salma Sabbour, Nivolumab + Plinabulin (NCT03575793)
- 2024-11-08Results posted on the registry: ETOP IBCSG Partners Foundation, Ipilimumab + Nivolumab (NCT02046733)
- 2024-10-31Results posted on the registry: Dana-Farber Cancer Institute, Nivolumab (480 mg infusion) + NeoVax plus Montanide (NCT03929029)
- 2024-10-16Results posted on the registry: National Cancer Institute (NCI), Blinatumomab + Ipilimumab (NCT02879695)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision