Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 01:15 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Controlled Ovarian Stimulation in Newly Diagnosed Breast Cancer PatiEnts (fAMHOPE)
NCT04289805 · Erasme University Hospital · PHASE4 · terminated · last registry update 2025-01-31 · Breast cancer · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The study had to be terminated due to the new European legislation on drug studies. This legislation requires all studies aimed at evaluating treatments to be registered as such, even in the context of Standard of Care.” | – | Registry record, Erasme University Hospital |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CYP19A1 in breast cancer within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-01-21Results posted on the registry: University of Chicago, Docetaxel + Herceptin (NCT03879577)
- 2026-01-16Phase 3 first posted: Shandong Suncadia Medicine Co., Ltd., HRS-8080 Tablets + Letrozole tablets (NCT07349069)
- 2026-01-14Phase 3 first posted: Rovi Pharmaceuticals Laboratories, Letrozole SIE + Ribociclib + Oral placebo + Oral Femara® + Ribociclib + Injectable placebo (NCT07340658)
- 2025-12-18Also stopped (terminated): Mario Negri Institute for Pharmacological Research, all-trans retinoic acid + Anastrozole 1mg (NCT04113863)
- 2025-12-09Results posted on the registry: Memorial Sloan Kettering Cancer Center, Vagifem® (vaginal 17β-estradiol) questionnaire & menopause symptom checklist (NCT00984399)
- 2025-11-10Results posted on the registry: Hoffmann-La Roche, Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (PD-L1) antibody + Bevacizumab (NCT03280563)
- 2025-10-22Results posted on the registry: Shayna Showalter, MD, tamoxifen, letrozole, anastrozole, or exemestane (NCT04272801)
- 2025-09-24Phase 3 first posted: Japanese Foundation for Cancer Research, Endocrine therapy + Abemaciclib + Endocrine Therapy (ET): letrozole, anastrozole, exemestane, tamoxifen (NCT07190443)
- 2025-09-18Also stopped (terminated): Sanofi, Amcenestrant (SAR439859) + Letrozole (NCT04191382)
- 2025-09-15Phase 3 first posted: Eli Lilly and Company, LY4064809 + Placebo (NCT07174336)
- 2025-09-11Also stopped (terminated): Sanofi, Amcenestrant-matching placebo + SAR439859 (NCT04478266)
- 2025-09-04Phase 3 first posted: Fudan University, Endocrine Therapy of Physician's Choice (NCT07153757)
- 2025-08-29Results posted on the registry: Arvinas Inc., ARV-471 + Anastrozole (NCT05549505)
- 2025-07-29Also stopped (terminated): University of Milano Bicocca, Abemaciclib + Aromatase Inhibitors (NCT04227327)
- 2025-07-25Phase 3 first posted: Olema Pharmaceuticals, Inc., Palazestrant + Letrozole-matching placebo (NCT07085767)
- 2025-07-14Phase 3 first posted: Pfizer, PF-07248144 + Fulvestrant (NCT07062965)
- 2025-07-11Results posted on the registry: Eli Lilly and Company, Imlunestrant + Exemestane (NCT04975308)
- 2025-07-11Phase 3 first posted: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Palbociclib 125mg qd (3 weeks of treatment followed by 1 week off) + Anastrozole 1mg qd / Letrozole 2.5mg qd / Exemestane 25mg qd + Palbociclib 125mg qd (3 weeks of treatment followed by 1 week off) + Anastrozole 1mg qd / Letrozole 2.5mg qd / Exemestane 25mg qd + Hydroxychloroquine 600mg bid (NCT07061717)
- 2025-06-24Results posted on the registry: Boehringer Ingelheim, Xentuzumab + Abemaciclib (NCT03099174)
- 2025-06-17Phase 3 first posted: Shandong Suncadia Medicine Co., Ltd., HRS-8080 Tablet + Fulvestrant injection (NCT07024173)
- 2025-06-13Phase 3 first posted: Fudan University, Endocrine Therapy (Tamoxifen, Anastrozol, Letrozole, Exemestane) + Standard endocrine therapy combined with CDK4/6 Inhibitor (NCT07019363)
- 2025-06-05Phase 3 first posted: Fudan University, Chemotherapy + CDK4/6 Inhibitor (NCT07005557)
- 2025-06-04Results posted on the registry: Institute of Cancer Research, United Kingdom, Anastrozole + Exemestane (NCT00253422)
- 2025-04-24Results posted on the registry: ECOG-ACRIN Cancer Research Group, anastrozole (NCT01824836)
- 2025-04-10Results posted on the registry: Inova Health Care Services, Biopsy-Guided Therapy Selection (NCT04965688)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision