Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 01:17 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
PK and Dose Escalation and Expansion Study of DST-2970
NCT04291664 · DisperSol Technologies, LLC · PHASE1 · terminated · last registry update 2024-10-17 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Dose escalation portion of the study completed, one expansion cohort was eliminated due to change in standard of care, and the second cohort was not enrolled based on future development considerations.” | – | Registry record, DisperSol Technologies, LLC |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CYP17A1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-10-14Results posted on the registry: Progenics Pharmaceuticals, Inc., I-131-1095 + Enzalutamide (NCT03939689)
- 2025-10-09Results posted on the registry: Novartis Pharmaceuticals, 177Lu-PSMA-617 + 68Ga-PSMA-11 (NCT04689828)
- 2025-10-09Phase 3 first posted: Amgen, Xaluritamig + Abiraterone acetate (NCT07213674)
- 2025-10-03Also stopped (terminated): University of Chicago, Abiraterone Oral Tablet + Prednisone tablet (NCT05276492)
- 2025-09-29Also stopped (withdrawn): Latin American Cooperative Oncology Group, Niraparib/Abirate rone acetate fixed-dose combination + Prednisone (NCT06527690)
- 2025-09-15Also stopped (terminated): Emory University, Abiraterone + Docetaxel (NCT05733351)
- 2025-09-12Results posted on the registry: Daniel George, MD, ARN-509 + Abiraterone Acetate (NCT03098836)
- 2025-08-01Results posted on the registry: VA Office of Research and Development, Leuprolide + apalutamide (NCT03298087)
- 2025-07-15Results posted on the registry: Boehringer Ingelheim, BI 836845 + Enzalutamide (NCT02204072)
- 2025-06-29Results posted on the registry: AstraZeneca, olaparib + abiraterone acetate (NCT05171816)
- 2025-06-27Results posted on the registry: Eli Lilly and Company, Abemaciclib + Abiraterone (NCT05288166)
- 2025-06-24Also stopped (terminated): Jiangsu HengRui Medicine Co., Ltd., SHR3680 + SHR3162 (NCT04102124)
- 2025-06-19Results posted on the registry: Cortendo AB, Levoketoconazole (NCT03621280)
- 2025-05-01Phase 3 first posted: AstraZeneca, Saruparib + Placebo (NCT06952803)
- 2025-04-13Also stopped (terminated): Centre hospitalier de l'Université de Montréal (CHUM), Cabazitaxel plus prednisone + Docetaxel plus prednisone (NCT03764540)
- 2025-04-08Results posted on the registry: Opna Bio LLC, PLX2853 20 mg + Olaparib (NCT04556617)
- 2025-04-08Also stopped (terminated): Opna Bio LLC, PLX2853 20 mg + Olaparib (NCT04556617)
- 2025-03-06Results posted on the registry: Eli Lilly and Company, Abemaciclib + Placebo (NCT03706365)
- 2025-03-03Phase 3 first posted: Novartis Pharmaceuticals, AAA817 + ARPI (NCT06855277)
- 2025-02-28Also stopped (terminated): ESSA Pharmaceuticals, EPI-7386 (QD) + EPI-7386 (BID) (NCT04421222)
- 2025-02-03Also stopped (terminated): Janssen Research & Development, LLC, EPI-7386 + Abiraterone Acetate (NCT05295927)
- 2025-01-27Results posted on the registry: M.D. Anderson Cancer Center, Abiraterone Acetate + Prednisone (NCT01254864)
- 2025-01-10Phase 3 first posted: Ding-Wei Ye, Abiraterone Acetate (II)+ prednisolone (5mg bid) +ADT + Abiraterone acetate 1000 mg + prednisolone (5mg bid) +ADT (NCT06768255)
- 2025-01-08Phase 3 first posted: Celgene, BMS-986365 + Enzalutamide (NCT06764485)
- 2024-12-11Results posted on the registry: MedSIR, radium-223 (NCT03002220)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision