Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 01:17 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Early Treatment With Evolocumab in Patients With ST-elevation Myocardial Infarction
NCT04303377 · Fondazione IRCCS Policlinico San Matteo di Pavia · PHASE2 · withdrawn · last registry update 2024-11-21 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The sponsor required early termination of the economic agreement due to a supposed extension of the enrollment period for bureaucracy reasons and for the concomitant Covid -19 Pandemic” | – | Registry record, Fondazione IRCCS Policlinico San Matteo di Pavia |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PCSK9 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-11-21Phase 3 first posted: Beijing Tiantan Hospital, High target group + Low target group (NCT07242599)
- 2025-10-23Results posted on the registry: Johns Hopkins University, Evolocumab + Placebos (NCT04082442)
- 2025-09-15Phase 3 first posted: Nanfang Hospital, Southern Medical University, PCSK9 inhibitor (NCT07174375)
- 2025-08-21Results posted on the registry: Novartis Pharmaceuticals, Inclisiran (NCT04873934)
- 2025-08-13Results posted on the registry: Novartis Pharmaceuticals, Inclisiran + Ezetimibe (NCT05763875)
- 2025-08-04Phase 3 first posted: Novartis Pharmaceuticals, Placebo + Inclisiran (NCT07102628)
- 2025-08-03Phase 3 first posted: LIB Therapeutics LLC, lerodalcibep 300 mg Monthly SC (NCT07102511)
- 2025-06-10Results posted on the registry: Novartis Pharmaceuticals, Inclisiran + Placebo (NCT04652726)
- 2025-06-08Results posted on the registry: Novo Nordisk A/S, NNC0385-0434 A 15 mg + NNC0385-0434 A 40 mg (NCT04992065)
- 2025-05-31Results posted on the registry: Novartis Pharmaceuticals, Inclisiran + Placebo (NCT04659863)
- 2025-04-20Results posted on the registry: Novartis Pharmaceuticals, Inclisiran + Matching Placebo for Inclisiran (NCT05888103)
- 2025-03-17Also stopped (withdrawn): University of Louisville, Statin + Aspirin tablet (NCT06280976)
- 2025-02-07Phase 3 first posted: Novartis Pharmaceuticals, Pelacarsen + Placebo (NCT06813911)
- 2025-01-27Also stopped (terminated): Monash University, a drug against PCSK9 (NCT05834673)
- 2024-11-20Phase 3 first posted: Xiang Luo, PCSK9 inhibitors combined with atorvastatin/rosuvastatin + Atorvastatin/Rosuvastatin (NCT06696820)
- 2024-10-17Results posted on the registry: NYU Langone Health, Statin + PCSK9 inhibitor (NCT04369664)
- 2024-09-19Phase 3 first posted: Novartis Pharmaceuticals, Inclisiran + Placebo (NCT06597006)
- 2024-09-19Phase 3 first posted: Novartis Pharmaceuticals, Inclisiran + Placebo (NCT06597019)
- 2024-09-19Results posted on the registry: Novartis Pharmaceuticals, Inclisiran (NCT04929249)
- 2024-08-23Phase 3 first posted: Hasten Biopharmaceutical Co., Ltd., Lerodalcibep + matching placebo (NCT06568471)
- 2024-08-06Also stopped (terminated): Imperial College London, Evolocumab + Placebo (NCT04073134)
- 2024-07-17Results posted on the registry: Cedars-Sinai Medical Center, Evolocumab + Omnipaque (NCT03689946)
- 2024-07-10Phase 3 first posted: Icahn School of Medicine at Mount Sinai, Inclisiran (NCT06494501)
- 2024-06-03Results posted on the registry: University of Nebraska, Evolocumab (NCT03944577)
- 2024-05-29Also stopped (terminated): Amgen, Evolocumab (NCT03080935)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision