Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 18:08 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Study of Hydroxycholoroquine Compared to Placebo as Treatment for People With COVID-19
NCT04379492 · Memorial Sloan Kettering Cancer Center · PHASE2 · withdrawn · last registry update 2025-05-16 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Emerging evidence does not support the use of HCQ for treatment or prevention of SARS -CoV2 infection. No pts have been enrolled.” | – | Registry record, Memorial Sloan Kettering Cancer Center |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against TLR7 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-05-14Also stopped (terminated): University of Utah, Hydroxychloroquine + Trametinib (NCT03825289)
- 2026-04-29Also stopped (terminated): Guy's and St Thomas' NHS Foundation Trust, Hydroxychloroquine + Placebo (NCT04316494)
- 2026-04-14Also stopped (terminated): University Hospital, Rouen, Hydroxychloroquine + placebo (NCT02595346)
- 2026-04-13Also stopped (terminated): Cancer Trials Ireland, Trametinib + Hydroxychloroquine (NCT05518110)
- 2026-04-06Also stopped (withdrawn): Assistance Publique - Hôpitaux de Paris, Plaquenil 200Mg Tablet + Placebo oral tablet (NCT04275778)
- 2026-03-27Also stopped (terminated): Incannex Healthcare Ltd, IHL-675A + Cannabidiol (NCT05942911)
- 2026-03-03Also stopped (suspended): National Institute of Allergy and Infectious Diseases (NIAID), CH505 TF chTrimer + 3M-052-AF (NCT06680479)
- 2026-02-27Results posted on the registry: National Institute of Allergy and Infectious Diseases (NIAID), CH505 TF chTrimer + 3M-05-AF (NCT04915768)
- 2026-02-06Also stopped (terminated): Queen's Medical Center, Hydroxychloroquine (NCT04345692)
- 2026-01-23Results posted on the registry: Emory University, Gemcitabine + Hydroxychloroquine (NCT04524702)
- 2026-01-21Phase 3 first posted: EMD Serono Research & Development Institute, Inc., Enpatoran + Placebo (NCT07355218)
- 2026-01-16Results posted on the registry: Gilead Sciences, Vesatolimod + VRC07523LS (NCT05281510)
- 2026-01-12Phase 3 first posted: EMD Serono Research & Development Institute, Inc., Enpatoran + Placebo (NCT07332481)
- 2025-12-04Phase 3 first posted: National Taiwan University Hospital, Hydrochloroquine + Placebo (NCT07265297)
- 2025-12-03Results posted on the registry: Matthias Griese, Hydroxychloroquine sulfate (NCT02615938)
- 2025-12-03Also stopped (terminated): Matthias Griese, Hydroxychloroquine sulfate (NCT02615938)
- 2025-12-01Results posted on the registry: EMD Serono Research & Development Institute, Inc., Enpatoran low dose + Enpatoran medium dose (NCT05162586)
- 2025-11-14Results posted on the registry: National Institute of Allergy and Infectious Diseases (NIAID), sD-NP-GT8 DNA + sD-NP-GT8 DNA (NCT05781542)
- 2025-09-25Results posted on the registry: BioMed Valley Discoveries, Inc, Ulixertinib + Hydroxychloroquine (NCT05221320)
- 2025-09-25Also stopped (terminated): BioMed Valley Discoveries, Inc, Ulixertinib + Hydroxychloroquine (NCT05221320)
- 2025-09-23Also stopped (terminated): Sanofi, Hydroxychloroquine SAR321068 + Placebo (NCT04333654)
- 2025-09-15Also stopped (withdrawn): London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's, Hydroxychloroquine + Placebo (NCT04397328)
- 2025-09-04Also stopped (suspended): National Institute of Allergy and Infectious Diseases (NIAID), 3M-052-AF + Alum + UVAX-1107 (NCT06905275)
- 2025-08-29Results posted on the registry: Milton S. Hershey Medical Center, Hydroxychloroquine + Placebo Oral Capsule (NCT03030118)
- 2025-07-11Phase 3 first posted: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Palbociclib 125mg qd (3 weeks of treatment followed by 1 week off) + Anastrozole 1mg qd / Letrozole 2.5mg qd / Exemestane 25mg qd + Palbociclib 125mg qd (3 weeks of treatment followed by 1 week off) + Anastrozole 1mg qd / Letrozole 2.5mg qd / Exemestane 25mg qd + Hydroxychloroquine 600mg bid (NCT07061717)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision