Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 00:38 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Perampanel Titration and Cognitive Effects
NCT04417907 · Kimford Jay Meador · PHASE4 · terminated · last registry update 2024-06-06 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study sponsor no longer provided funding.” | – | Registry record, Kimford Jay Meador |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against GRIA4 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-05-31Also stopped (withdrawn): Janey Pratt, Topiramate + Phentermine (NCT04572217)
- 2025-05-23Results posted on the registry: University of Colorado, Denver, Phentermine + Immediate Release Topiramate (NCT04095104)
- 2025-04-11Also stopped (withdrawn): Stanford University, Topamax + Gabapentin (NCT04613024)
- 2025-02-28Also stopped (terminated): VA Office of Research and Development, a drug against GRIA4 (NCT04581603)
- 2025-02-14Also stopped (withdrawn): University of California, Los Angeles, Medical weight loss (NCT05812183)
- 2025-01-28Also stopped (suspended): University of Sao Paulo, Carbamazepine-Implant + Topiramate-Implant (NCT03307863)
- 2024-10-16Results posted on the registry: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Propranolol + Pindolol (NCT01950520)
- 2024-09-19Also stopped (terminated): The Cleveland Clinic, Phentermine / Topiramate Extended Release Oral Capsule + naltrexone/bupropion extended-release (NCT04531176)
- 2024-08-05Results posted on the registry: Dana-Farber Cancer Institute, Perampanel + Standard of Care (NCT04497142)
- 2024-07-31Results posted on the registry: University of Florida, Fycompa + Fycompa with a boost (NCT05201703)
- 2024-07-31Also stopped (terminated): University of Florida, Fycompa + Fycompa with a boost (NCT05201703)
- 2024-07-22Results posted on the registry: The Cleveland Clinic, Phentermine / Topiramate Extended Release Oral Capsule + naltrexone/bupropion extended-release (NCT04531176)
- 2024-06-18Results posted on the registry: VIVUS LLC, VI-0521 + Phentermine (NCT05215418)
- 2024-06-11Results posted on the registry: Kristin R Hoffman, Topiramate + Placebo (NCT01765218)
- 2024-06-11Also stopped (terminated): Kristin R Hoffman, Topiramate + Placebo (NCT01765218)
- 2024-04-19Results posted on the registry: Massachusetts General Hospital, Topiramate or Placebo (NCT00606411)
- 2024-04-04Phase 3 first posted: Kafrelsheikh University, Zonisamide 50 MG + Topiramate 50 MG (NCT06347497)
- 2024-02-08Phase 3 first posted: Kafrelsheikh University, Valproic acid + Topiramate 50 MG (NCT06248931)
- 2024-02-06Phase 3 first posted: Kafrelsheikh University, Lacosamide 50 MG + Topiramate 50Mg Tab (NCT06243692)
- 2023-12-14Also stopped (terminated): Assistance Publique - Hôpitaux de Paris, Perampanel + Placebo (NCT04309721)
- 2023-11-18Results posted on the registry: VA Office of Research and Development, topiramate + placebo (NCT03176953)
- 2023-11-14Results posted on the registry: Virginia Commonwealth University, topiramate (NCT02878798)
- 2023-10-26Also stopped (withdrawn): University of Minnesota, Qsymia and lifestyle management therapy (NCT05834062)
- 2023-09-15Results posted on the registry: Eisai Inc., perampanel (NCT02914314)
- 2023-08-18Results posted on the registry: Virginia Commonwealth University, Perampanel + Placebo (NCT02120365)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision