Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:06 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Impact of Metformin on Immuno-virologic Parameters in HIV
NCT04500678 · University of Hawaii · PHASE2/PHASE3 · terminated · last registry update 2026-10-20 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “During the COVID pandemic, our IRB halted enrollment into the study among other changes. Post COVID it was decided that too long an interval between patient enrollment was problematic for the study and a discussion was made to terminate.” | – | Registry record, University of Hawaii |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against MT-ND6 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
No results, stops or Phase 3 starts on the same target in that window.
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision