Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 02:13 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium
NCT04513314 · University of Miami · PHASE4 · withdrawn · last registry update 2023-03-31 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “coronavirus omicron variant infection typically not associated with delirium and agitation severely hampered recruitment.” | – | Registry record, University of Miami |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against ALDH5A1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2024-03-13Also stopped (terminated): Cerebral Therapeutics LLC, Valproic Acid delivered to ICV (NCT04529954)
- 2024-02-08Phase 3 first posted: Kafrelsheikh University, Valproic acid + Topiramate 50 MG (NCT06248931)
- 2023-08-03Phase 3 first posted: Dr. Inge Winter, Escitalopram + Sertraline (NCT05973786)
- 2023-05-17Results posted on the registry: Universidad Autonoma de San Luis Potosí, Valproate Sodium + Memantine (NCT04698525)
- 2023-05-17Results posted on the registry: Intra-Cellular Therapies, Inc., Lumateperone (ITI-007) + Placebo (NCT02600507)
- 2023-02-10Phase 3 first posted: Tanta University, Levetiracetam &/or sodium valproate + Metformin (NCT05722951)
- 2022-11-14Results posted on the registry: Frequency Therapeutics, FX-322 + Placebo (NCT03616223)
- 2022-11-02Phase 3 first posted: Dr. Inge Winter, Clozapine + Esketamine Nasal Product (NCT05603104)
- 2022-06-27Also stopped (withdrawn): Assistance Publique Hopitaux De Marseille, Perampanel + conventional antiepileptic treatment (NCT03636958)
- 2022-06-24Phase 3 first posted: M.D. Anderson Cancer Center, Haloperidol + Chlorpromazine (NCT05431595)
- 2022-05-18Also stopped (withdrawn): Centers for Disease Control and Prevention, Pyridoxine + Sodium Valproate (NCT01730313)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision