Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 20:02 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
EMI-EHP Weight Management and Type 2 Diabetes Pragmatic Trial
NCT04531176 · The Cleveland Clinic · PHASE4 · terminated · last registry update 2024-09-19 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “After an unplanned yet IRB approved interim analysis, it was found that there was not a significant difference between the 3 arms of the study. The study was closed due to futility. All Patients are off study and this study will not resume.” | – | Registry record, The Cleveland Clinic |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against GLP1R within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-09-10Phase 3 first posted: Eli Lilly and Company, Tirzepatide + Retatrutide (NCT07165028)
- 2025-07-18Results posted on the registry: Eli Lilly and Company, Bimagrumab + Semaglutide (NCT05616013)
- 2025-07-14Phase 3 first posted: BrightGene Bio-Medical Technology Co., Ltd., BGM0504 + BGM0504 (NCT07064486)
- 2025-07-10Phase 3 first posted: Ottawa Heart Institute Research Corporation, Semaglutide + Nicotine replacement (NCT07059377)
- 2025-07-08Results posted on the registry: Novo Nordisk A/S, Semaglutide + Placebo (semaglutide) (NCT04560998)
- 2025-06-24Phase 3 first posted: Eli Lilly and Company, Retatrutide + Placebo (NCT07035093)
- 2025-06-15Phase 3 first posted: University of Colorado, Denver, Semaglutide 1.7mg subcutaneous + Placebo (NCT07021937)
- 2025-06-09Phase 3 first posted: Novo Nordisk A/S, CagriSema (Cagrilintide B and Semaglutide I) + Placebo matched to CagriSema (Cagrilintide B and Semaglutide I) (NCT07011667)
- 2025-05-16Phase 3 first posted: University of Colorado, Denver, Metformin + semaglutide (NCT06975111)
- 2025-04-22Phase 3 first posted: Eli Lilly and Company, Mirikizumab + Mirikizumab (NCT06937086)
- 2025-04-22Phase 3 first posted: Eli Lilly and Company, Mirikizumab + Mirikizumab (NCT06937099)
- 2025-04-18Phase 3 first posted: Children's Hospital Los Angeles, Semaglutide 2.4 mg (NCT06934655)
- 2025-04-06Phase 3 first posted: University Health Network, Toronto, Semaglutide 0.25 mg + Semaglutide 0.5 mg (NCT06913023)
- 2025-03-26Phase 3 first posted: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, Metformin with Semaglutide (NCT06896981)
- 2025-01-17Results posted on the registry: Novo Nordisk A/S, IcoSema + Semaglutide 1 mg (NCT05259033)
- 2025-01-16Phase 3 first posted: Gan & Lee Pharmaceuticals., GZR18 + semaglutide (NCT06778967)
- 2024-12-24Phase 3 first posted: Amylyx Pharmaceuticals Inc., Avexitide (NCT06747468)
- 2024-12-18Phase 3 first posted: Chia Tai Tianqing Pharmaceutical Group Co., Ltd., TQF3510 (Semaglutide Injection) + Wegovy® (NCT06738979)
- 2024-12-18Phase 3 first posted: Eli Lilly and Company, Dulaglutide (NCT06739122)
- 2024-12-04Phase 3 first posted: BrightGene Bio-Medical Technology Co., Ltd., Drug: 5 mg BGM0504 Administered SC + Drug:10 mg BGM0504 Administered SC (NCT06716216)
- 2024-10-28Phase 3 first posted: Eli Lilly and Company, Retatrutide + Tirzepatide (NCT06662383)
- 2024-10-18Phase 3 first posted: Fujian Shengdi Pharmaceutical Co., Ltd., HRS9531 Injection + Semaglutide Injection (NCT06649344)
- 2024-10-09Phase 3 first posted: Boehringer Ingelheim, Survodutide + Placebo matching survodutide (NCT06632457)
- 2024-10-09Phase 3 first posted: Boehringer Ingelheim, Survodutide + Placebo (NCT06632444)
- 2024-09-19Phase 3 first posted: Eli Lilly and Company, Ixekizumab + Tirzepatide (NCT06588283)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision