Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 05:00 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients
NCT04539236 · Mikkael Sekeres, MD · PHASE1/PHASE2 · suspended · last registry update 2026-07-17 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Funding Sponsor decision” | – | Registry record, Mikkael Sekeres, MD |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against TGFB1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-10-26Phase 3 first posted: Institute of Hematology & Blood Diseases Hospital, China, Luspatercept (NCT07894861)
- 2026-09-03Also stopped (terminated): Forma Therapeutics, Inc., Etavopivat (NCT05568225)
- 2026-07-16Results posted on the registry: Celgene, ACE-536 (NCT04717414)
- 2026-06-09Phase 3 first posted: Nanfang Hospital, Southern Medical University, Luspatercept + Epoetin (NCT07636486)
- 2026-06-04Also stopped (withdrawn): Peking Union Medical College Hospital, Luspatercept + cyclosporine (NCT06424639)
- 2026-05-04Results posted on the registry: EMD Serono Research & Development Institute, Inc., M6223 + Bintrafusp alfa (NCT04457778)
- 2026-04-20Phase 3 first posted: Nanfang Hospital, Southern Medical University, Luspatercept (NCT07539779)
- 2026-03-18Results posted on the registry: M.D. Anderson Cancer Center, Bintrafusp Alfa + Pimasertib (NCT04789668)
- 2026-03-18Also stopped (terminated): M.D. Anderson Cancer Center, Bintrafusp Alfa + Pimasertib (NCT04789668)
- 2026-02-02Results posted on the registry: EMD Serono Research & Development Institute, Inc., Bintrafusp alfa (NCT05061823)
- 2025-12-23Results posted on the registry: Fundación GECP, Bintrafusp alfa (NCT05005429)
- 2025-11-17Results posted on the registry: Mayo Clinic, Bintrafusp Alfa + Docetaxel (NCT04396535)
- 2025-11-17Also stopped (terminated): Mayo Clinic, Bintrafusp Alfa + Docetaxel (NCT04396535)
- 2025-10-22Results posted on the registry: Forma Therapeutics, Inc., Etavopivat (NCT05568225)
- 2025-08-08Results posted on the registry: National Cancer Institute (NCI), Bintrafusp alfa/M7824 + Ibuprofen (NCT05012098)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision