Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 06:04 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Study of TAS0612 in Participants With Advanced or Metastatic Solid Tumor Cancer
NCT04586270 · Taiho Oncology, Inc. · PHASE1 · terminated · last registry update 2025-03-13 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Taiho Oncology as the sponsor of study TAS0612-101, has made a strategic decision to terminate the TAS0612-101 study, taking into consideration the safety profile of TAS0612 and the absence of encouraging anti-tumor activity.” | – | Registry record, Taiho Oncology, Inc. |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against AKT2 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-02-25Also stopped (terminated): Gordon Mills, MD, PhD, Capivasertib + Ceralasertib (NCT03801369)
- 2026-02-02Results posted on the registry: AstraZeneca, Durvalumab + Capivasertib (NCT03742102)
- 2026-01-28Results posted on the registry: Canadian Cancer Trials Group, Ipatasertib + Fulvestrant (NCT04650581)
- 2025-12-24Also stopped (withdrawn): Imperial College London, Capivasertib (NCT06613516)
- 2025-12-19Results posted on the registry: National Cancer Institute (NCI), Carboplatin + Ipatasertib (NCT05276973)
- 2025-12-15Phase 3 first posted: Women's Cancer Study Group GmbH, Capivasertib (NCT07281833)
- 2025-12-01Also stopped (terminated): Gustave Roussy, Cancer Campus, Grand Paris, Atezolizumab Injection + Bevacizumab (NCT05180006)
- 2025-11-21Results posted on the registry: Gordon Mills, MD, PhD, Capivasertib + Ceralasertib (NCT03801369)
- 2025-11-10Results posted on the registry: Hoffmann-La Roche, Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (PD-L1) antibody + Bevacizumab (NCT03280563)
- 2025-10-27Results posted on the registry: AstraZeneca, Fulvestrant + Capivasertib (NCT04305496)
- 2025-09-23Results posted on the registry: National Cancer Institute (NCI), Capivasertib + Cediranib Maleate (NCT03660826)
- 2025-08-26Results posted on the registry: National Cancer Institute (NCI), Ipatasertib (NCT06400251)
- 2025-05-28Results posted on the registry: Rutgers, The State University of New Jersey, a drug against AKT2 (NCT03326713)
- 2025-05-21Phase 3 first posted: Relay Therapeutics, Inc., Zovegalisib + Capivasertib (NCT06982521)
- 2025-04-18Results posted on the registry: University of Arkansas, a drug against AKT2 (NCT04064567)
- 2025-01-08Phase 3 first posted: AstraZeneca, Fulvestrant + Capivasertib (NCT06764186)
- 2025-01-08Results posted on the registry: Genentech, Inc., Entrectinib + Inavolisib (NCT04632992)
- 2024-11-08Results posted on the registry: Hoffmann-La Roche, Ipatasertib + Placebo (NCT04060862)
- 2024-11-08Also stopped (terminated): Hoffmann-La Roche, Ipatasertib + Placebo (NCT04060862)
- 2024-10-30Results posted on the registry: Hoffmann-La Roche, Ipatasertib + Paclitaxel (NCT03800836)
- 2024-10-10Phase 3 first posted: AstraZeneca, Capivasertib + Fulvestrant (NCT06635447)
- 2024-06-20Results posted on the registry: AstraZeneca, Capivasertib (NCT05008055)
- 2024-06-14Results posted on the registry: Hoffmann-La Roche, Alectinib + Vismodegib (NCT03498521)
- 2024-06-04Also stopped (terminated): Merck Sharp & Dohme LLC, MK-2206 + Trastuzumab (NCT00963547)
- 2024-03-27Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Ipatasertib (NCT04177108)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision