Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 02:16 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study
NCT04600921 · Medical University of Graz · PHASE3 · terminated · last registry update 2025-06-03 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The feasibility (recruitment) of the high number of patients (402 patients with HFrEF or HFmrEF) was impossible due to the rapid increase in SGLT2 inhibitors in patients with heart failure.” | – | Registry record, Medical University of Graz |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against SLC5A2 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-06-03Phase 3 first posted: AstraZeneca, Balcinrenone/dapagliflozin + Dapagliflozin (NCT07624305)
- 2026-05-20Phase 3 first posted: Chittagong Medical College, Dapagliflozin +Finerenone arm + Dapagliflozin arm (NCT07598864)
- 2026-05-15Phase 3 first posted: Ain Shams University, Empagliflozin (EMPA) (NCT07591077)
- 2026-05-14Phase 3 first posted: Dr Mudassar Saeed Pansota, ARBs alone + ARBs in combination of SGLT2i (NCT07586371)
- 2026-05-13Also stopped (terminated): Washington University School of Medicine, Carvedilol + Empagliflozin (NCT06844669)
- 2026-05-08Results posted on the registry: University of Chicago, SGLT2i (NCT05278962)
- 2026-05-06Phase 3 first posted: Washington University School of Medicine, HFrEF Polypill (NCT07569640)
- 2026-04-16Phase 3 first posted: King's College London, Empagliflozin 10mg OD (NCT07533747)
- 2026-04-16Also stopped (terminated): Department of Nephrology Clinic Ottakring Vienna, a drug against SLC5A2 (NCT06094231)
- 2026-04-15Results posted on the registry: Amsterdam UMC, location VUmc, Ertugliflozin 15 mg (NCT05727579)
- 2026-03-30Also stopped (terminated): The George Institute, Dapagliflozin 10mg Tab + Placebo (NCT05468203)
- 2026-03-23Phase 3 first posted: University Hospital, Strasbourg, France, Dapaglifozin + Placebo (NCT07488689)
- 2026-03-13Phase 3 first posted: Hospital de Clinicas de Porto Alegre, Furosemide 40 Milligrams. + Furosemide 40 Milligrams. (NCT07469722)
- 2026-02-27Also stopped (terminated): Duke University, Empagliflozin10Mg Tab + Placebo (NCT04906213)
- 2026-02-20Also stopped (withdrawn): University Hospital, Basel, Switzerland, empagliflozin + anakinra (NCT05174507)
- 2026-02-11Results posted on the registry: Boston University, Dapagliflozin (NCT05139914)
- 2026-02-11Also stopped (terminated): Boston University, Dapagliflozin (NCT05139914)
- 2026-02-06Phase 3 first posted: Michael Mæng, Intensified medical follow-up and glucose-lowering drugs (NCT07392151)
- 2026-01-30Phase 3 first posted: Hanmi Pharmaceutical Company Limited, HM11260C + Placebo (NCT07379333)
- 2026-01-28Results posted on the registry: Mayo Clinic, Sitagliptin + Dapagliflozin (NCT06263673)
- 2026-01-21Phase 3 first posted: kewen Chen,MD, Experimental Group + Control (Standard treatment) (NCT07356388)
- 2026-01-20Results posted on the registry: AstraZeneca, Placebo (placebo matching zibotentan capsule and placebo matching dapagliflozin tablet) + Zibotentan + placebo (placebo matching dapagliflozin tablet) (NCT06269484)
- 2026-01-15Phase 3 first posted: Mansoura University, Dapagliflozin (10Mg Tab) along with standard medical therapy (NCT07344922)
- 2025-12-22Phase 3 first posted: Instituto Mexicano del Seguro Social, Dapagliflozin 10 MG Oral Tablet + Semaglutide (Rybelsus®) (NCT07297589)
- 2025-12-19Phase 3 first posted: Instituto Mexicano del Seguro Social, Dapagliflozin 10 MG Oral Tablet + Semaglutide (Rybelsus®) (NCT07295223)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision