Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:37 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Study to Investigate the Use of Benralizumab in Patients With Chronic Spontaneous Urticaria Who Are Symptomatic Despite the Use of Antihistamines (ARROYO)
NCT04612725 · AstraZeneca · PHASE2 · terminated · last registry update 2024-03-13 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study did not meet primary endpoint” | – | Registry record, AstraZeneca |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against IL5RA within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-01-14Results posted on the registry: AstraZeneca, Benralizumab + Mepolizumab (NCT04157348)
- 2025-01-09Results posted on the registry: AstraZeneca, Symbicort® + Fasenra® (NCT04159519)
- 2024-12-27Phase 3 first posted: AstraZeneca, ICS-LABA + benralizumab (NCT06750289)
- 2024-12-11Results posted on the registry: AstraZeneca, Benralizumab (NCT05384938)
- 2024-11-29Results posted on the registry: AstraZeneca, Benralizumab + Placebo (NCT04612790)
- 2024-11-29Also stopped (terminated): AstraZeneca, Benralizumab + Placebo (NCT04612790)
- 2024-08-29Results posted on the registry: Memorial Sloan Kettering Cancer Center, Benralizumab + fulvestrant or AIs) and PI3K inhibition (alpelisib) (NCT05966584)
- 2024-08-29Also stopped (terminated): Memorial Sloan Kettering Cancer Center, Benralizumab + fulvestrant or AIs) and PI3K inhibition (alpelisib) (NCT05966584)
- 2024-07-22Phase 3 first posted: AstraZeneca, Benralizumab (NCT06512883)
- 2024-06-18Phase 3 first posted: AstraZeneca, Benralizumab (NCT06465485)
- 2024-04-24Results posted on the registry: AstraZeneca, Benralizumab + Placebo (NCT03186209)
- 2024-01-08Also stopped (withdrawn): Charite University, Berlin, Germany, Fasenra Prefilled Syringe (NCT05528913)
- 2023-11-18Results posted on the registry: AstraZeneca, Benralizumab + Matching placebo (NCT04543409)
- 2023-11-18Also stopped (terminated): AstraZeneca, Benralizumab + Matching placebo (NCT04543409)
- 2023-08-31Also stopped (terminated): AstraZeneca, Benralizumab + Placebo / Benralizumab (NCT04605094)
- 2023-06-27Results posted on the registry: AstraZeneca, Benralizumab + Placebo / Benralizumab (NCT04605094)
- 2023-05-18Results posted on the registry: AstraZeneca, Benralizumab (NCT04305405)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision