Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:42 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Levosimendan In Ambulatory Heart Failure Patients
NCT04705337 · Medical University of Bialystok · PHASE4 · terminated · last registry update 2025-05-09 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The level of recruitment, 62 participants enrolled, does not allow for achieving the protocol-defined target of 350 participants by the end of the recruitment period.” | – | Registry record, Medical University of Bialystok |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PDE3A within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-04-22Results posted on the registry: Tenax Therapeutics, Inc., Levosimendan (NCT03624010)
- 2026-03-30Phase 3 first posted: Beni-Suef University, pentoxifylline 400 mg (NCT07499817)
- 2026-02-27Phase 3 first posted: Tenax Therapeutics, Inc., TNX-103 (NCT07436689)
- 2025-12-17Phase 3 first posted: Tenax Therapeutics, Inc., TNX-103 + Placebo (NCT07288398)
- 2025-12-04Phase 3 first posted: Chittagong Medical College, Levosimendan (NCT07262723)
- 2025-11-06Results posted on the registry: NICHD Neonatal Research Network, Milrinone + Placebo (5% Dextrose) (NCT02951130)
- 2025-08-28Phase 3 first posted: Centre Hospitalier St Anne, Cilostazol (Pletal®) 100 mg Tablets + Placebo (NCT07144956)
- 2025-06-11Results posted on the registry: Al-Azhar University, combination of Pentoxifylline 400 MG and Folic Acid + folic acid (NCT05284656)
- 2025-05-31Also stopped (withdrawn): Cedars-Sinai Medical Center, Pentoxifylline Oral Product + Placebo (NCT04391231)
- 2025-05-22Also stopped (terminated): Prokrea BCN, S.L., Vaginal product (NCT06986031)
- 2025-05-14Also stopped (suspended): Sclnow Biotechnology Co., Ltd., Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#) + conventional treatment (NCT03180450)
- 2025-05-11Results posted on the registry: Peng Roc Chen, MD, Nicardipine + Verapamil (NCT01996436)
- 2025-05-11Also stopped (terminated): Peng Roc Chen, MD, Nicardipine + Verapamil (NCT01996436)
- 2025-04-18Results posted on the registry: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA, Ensifentrine 3 mg twice daily (NCT06460493)
- 2024-11-27Results posted on the registry: University of California, Los Angeles, Ibudilast + Placebo oral capsule (NCT03594435)
- 2024-11-12Phase 3 first posted: Ain Shams University, Melatonin (NCT06685679)
- 2024-11-08Phase 3 first posted: NICHD Neonatal Research Network, Milrinone infusion + Placebo infusion (NCT06679855)
- 2024-10-30Results posted on the registry: MediciNova, Ibudilast + Placebo (NCT04429555)
- 2024-10-23Also stopped (terminated): Niguarda Hospital, Early intra-aortic balloon pump (IABP) implantation (NCT04369573)
- 2024-10-15Results posted on the registry: University of Missouri-Columbia, Pentoxifylline + Placebo (NCT02592863)
- 2024-10-15Also stopped (terminated): University of Missouri-Columbia, Pentoxifylline + Placebo (NCT02592863)
- 2024-10-01Results posted on the registry: Philips Clinical & Medical Affairs Global, a drug against PDE3A (NCT04696354)
- 2024-09-25Also stopped (terminated): Iain Bressendorff, ACEi / ARB, SGLT2i, finerenone, semaglutide, pentoxifylline, hydrochlorthiazide, baricitinib (NCT05897372)
- 2024-09-24Results posted on the registry: MediciNova, ibudilast + Ibudilast (NCT02714036)
- 2024-06-27Phase 3 first posted: Ain Shams University, levosemindan (NCT06478667)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision