Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:01 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Study of Ociperlimab With Tislelizumab Compared to Pembrolizumab in Participants With Untreated Lung Cancer
NCT04746924 · BeiGene · PHASE3 · terminated · last registry update 2026-05-12 · Non-small cell lung cancer · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “This decision was conducted by the sponsor based on lack of efficacy and not driven by safety concerns.” | Open Targets' class: negative | Registry record, BeiGene |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PDCD1 in non-small cell lung cancer within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-11-04Results posted on the registry: Duke University, Alirocumab and Cemiplimab (NCT05553834)
- 2026-11-04Phase 3 first posted: Assistance Publique - Hôpitaux de Paris, a drug against PDCD1 (NCT07915037)
- 2026-11-02Also stopped (withdrawn): CureVac, CV09070101 mRNA vaccine (CVHNLC) 50 µg + CV09070101 mRNA vaccine (CVHNLC) 100 µg (NCT07073183)
- 2026-11-02Also stopped (withdrawn): Genmab, Petosemtamab + Pembrolizumab (NCT07353957)
- 2026-10-29Results posted on the registry: Merck Sharp & Dohme LLC, Pembrolizumab + MK-4830 (NCT04165083)
- 2026-10-28Results posted on the registry: Immedica Pharma AB, Pegzilarginase + Pembrolizumab (NCT03371979)
- 2026-10-28Also stopped (terminated): Immedica Pharma AB, Pegzilarginase + Pembrolizumab (NCT03371979)
- 2026-08-20Phase 3 first posted: Revolution Medicines, Inc., zoldonrasib + Placebo (NCT07777822)
- 2026-08-10Phase 3 first posted: AbbVie, ABBV-1480 + Pembrolizumab (NCT07756645)
- 2026-07-20Phase 3 first posted: AIO-Studien-gGmbH, Tislelizumab + Tislelizumab Combined With Chemotherapy (NCT07715396)
- 2026-04-21Phase 3 first posted: Hoffmann-La Roche, Divarasib + Pembrolizumab (NCT07541170)
- 2026-04-07Phase 3 first posted: Merck Sharp & Dohme LLC, Intismeran + Pembrolizumab coformulated with berahyaluronidase alfa (NCT07513376)
- 2026-02-25Phase 3 first posted: Merck Sharp & Dohme LLC, Calderasib + MK-3475A (NCT07431827)
- 2026-01-26Phase 3 first posted: Eikon Therapeutics, EIK1001 + Pembrolizumab (KEYTRUDA®) (NCT07365319)
- 2026-01-23Phase 3 first posted: Bristol-Myers Squibb, Pumitamig + Pembrolizumab (NCT07361510)
- 2025-09-29Phase 3 first posted: Boehringer Ingelheim, Zongertinib + Pembrolizumab (NCT07195695)
- 2025-09-24Phase 3 first posted: Merck Sharp & Dohme LLC, Calderasib + Pembrolizumab (+) Berahyaluronidase alfa (NCT07190248)
- 2025-09-09Phase 3 first posted: Qilu Pharmaceutical Co., Ltd., QL2107 + Keytruda® (NCT07162883)
- 2025-07-14Phase 3 first posted: Bristol-Myers Squibb, BMS-986504 + Pembrolizumab (NCT07063745)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision