Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:27 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Study of Pralsetinib Versus Standard of Care (SOC) for Treatment of RET-Mutated Medullary Thyroid Cancer (MTC).
NCT04760288 · Hoffmann-La Roche · PHASE3 · withdrawn · last registry update 2024-01-05 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Due to several logistical challenges during start-up which could not be overcome study was withdrawn.” | – | Registry record, Hoffmann-La Roche |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against RET within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2024-12-10Phase 3 first posted: Sun Yat-sen University, axitinib ± immune checkpoint inhibitors (ICIs), lenvatinib ± ICIs, cabozantinib ± ICIs, sunitinib and pazopanib (NCT06726421)
- 2024-10-29Results posted on the registry: Pfizer, Avelumab (MSB0010718C) + Axitinib (AG-013736) (NCT02684006)
- 2024-10-02Phase 3 first posted: Hoffmann-La Roche, Alectinib + Cisplatin (NCT06624059)
- 2024-09-19Results posted on the registry: National Cancer Institute (NCI), Cediranib + Sunitinib (NCT01391962)
- 2024-08-29Phase 3 first posted: Daiichi Sankyo, Quizartinib + Placebo (NCT06578247)
- 2024-08-26Results posted on the registry: Hoffmann-La Roche, Alectnib + Cisplatin (NCT03456076)
- 2024-07-23Results posted on the registry: Bayer, Regorafenib, (Stivarga, BAY73-4506) + Nivolumab (Opdivo) (NCT04704154)
- 2024-06-20Results posted on the registry: Eli Lilly and Company, Selpercatinib + Carboplatin (NCT04194944)
- 2024-06-14Results posted on the registry: Hoffmann-La Roche, Alectinib + Vismodegib (NCT03498521)
- 2024-06-13Results posted on the registry: Loxo Oncology, Inc., Selpercatinib + Cabozantinib (NCT04211337)
- 2024-05-29Results posted on the registry: Roswell Park Cancer Institute, Pembrolizumab + Sorafenib Tosylate (NCT03211416)
- 2024-04-09Results posted on the registry: Merck Sharp & Dohme LLC, pembrolizumab + lenvatinib (NCT04776148)
- 2024-02-28Results posted on the registry: M.D. Anderson Cancer Center, Azacitidine + Cytarabine (NCT01892371)
- 2024-01-10Phase 3 first posted: Suzhou Suncadia Biopharmaceuticals Co., Ltd., SHR-A1811 + TAS-102, Regorafenib , Fruquintinib (NCT06199973)
- 2024-01-02Results posted on the registry: Deciphera Pharmaceuticals, LLC, Ripretinib + Sunitinib (NCT03673501)
- 2023-11-21Results posted on the registry: National Cancer Institute (NCI), Alectinib + Brigatinib (NCT03737994)
- 2023-11-15Results posted on the registry: Dana-Farber Cancer Institute, Regorafenib (NCT02657551)
- 2023-10-10Phase 3 first posted: The Second Affiliated Hospital of Kunming Medical University, a drug against RET (NCT06073730)
- 2023-08-14Phase 3 first posted: Medicine Invention Design, Inc, ALECENSA - alectinib hydrochloride capsule (NCT05987956)
- 2023-07-03Results posted on the registry: Radiation Therapy Oncology Group, Sorafenib (NCT01730937)
- 2023-06-18Results posted on the registry: AstraZeneca, Durvalumab + Tremelimumab (Regimen 1) (NCT03298451)
- 2023-05-30Results posted on the registry: Bayer, Pembrolizumab + Regorafenib (Stivarga, BAY73-4506) (NCT04696055)
- 2023-03-15Phase 3 first posted: Cancer Research UK, Alectinib (NCT05770037)
- 2023-02-17Phase 3 first posted: Deciphera Pharmaceuticals, LLC, Ripretinib + Sunitinib (NCT05734105)
- 2023-02-10Phase 3 first posted: Cancer Research UK, Alectinib + Atezolizumab (NCT05722886)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision