Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 16:18 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Study of Sabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS Participants
NCT04812548 · Novartis Pharmaceuticals · PHASE2 · terminated · last registry update 2025-10-09 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study was stopped following a strategic decision from the Sponsor. It was not based on any safety findings or safety concerns with sabatolimab.” | – | Registry record, Novartis Pharmaceuticals |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against HAVCR2 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-07-01Results posted on the registry: GlaxoSmithKline, Cobolimab + Dostarlimab (NCT04655976)
- 2026-03-27Results posted on the registry: Hoffmann-La Roche, Lomvastomig + Tobemstomig (NCT04785820)
- 2026-02-27Results posted on the registry: Massachusetts General Hospital, MBG453 (NCT04823624)
- 2026-01-13Also stopped (terminated): Novartis Pharmaceuticals, MBG453 + Placebo (NCT03946670)
- 2026-01-13Also stopped (terminated): Novartis Pharmaceuticals, MBG453 + Venetoclax (NCT04150029)
- 2026-01-13Also stopped (terminated): Novartis Pharmaceuticals, Sabatolimab + Azacitidine (NCT04266301)
- 2025-12-12Results posted on the registry: Novartis Pharmaceuticals, Sabatolimab + Azacitidine (NCT04266301)
- 2025-11-17Results posted on the registry: Novartis Pharmaceuticals, MBG453 + Venetoclax (NCT04150029)
- 2025-10-16Also stopped (terminated): Novartis Pharmaceuticals, Sabatolimab + Azacitidine (NCT04623216)
- 2025-10-16Also stopped (terminated): Novartis Pharmaceuticals, MBG453 + Azacitidine (NCT04878432)
- 2025-10-10Also stopped (terminated): Novartis Pharmaceuticals, HDM201 + MBG453 (NCT03940352)
- 2025-10-10Also stopped (terminated): Novartis Pharmaceuticals, MBG453 + NIS793 (NCT04810611)
- 2025-08-20Results posted on the registry: Hoffmann-La Roche, Lomvastomig (NCT03708328)
- 2025-08-07Results posted on the registry: Novartis Pharmaceuticals, Ruxolitinib + Siremadlin (NCT04097821)
- 2025-08-07Also stopped (terminated): Novartis Pharmaceuticals, Ruxolitinib + Siremadlin (NCT04097821)
- 2025-07-31Results posted on the registry: Novartis Pharmaceuticals, MBG453 + Azacitidine (NCT04878432)
- 2025-06-03Results posted on the registry: Novartis Pharmaceuticals, Sabatolimab + Azacitidine (NCT04623216)
- 2024-12-27Results posted on the registry: GlaxoSmithKline, feladilimab (GSK3359609) + GSK3174998 (NCT02723955)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision