Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 07:05 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/Navocaftor/ABBV-119 or Galicaftor/Navocaftor/ABBV-576 Combination Therapies in Adult Participants With Cystic Fibrosis
NCT04853368 · AbbVie · PHASE2 · terminated · last registry update 2024-07-16 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Strategic considerations” | – | Registry record, AbbVie |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CFTR within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-05-18Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04183790)
- 2025-04-16Results posted on the registry: University of Alabama at Birmingham, Symdeko + Ivacaftor and Symdeko (NCT03624101)
- 2025-04-16Also stopped (terminated): University of Alabama at Birmingham, Symdeko + Ivacaftor and Symdeko (NCT03624101)
- 2025-03-06Results posted on the registry: Novartis Pharmaceuticals, QBW251 + Placebo (NCT04396366)
- 2024-12-06Phase 3 first posted: Napo Pharmaceuticals, Inc., Crofelemer Powder for Oral Solution + Placebo Powder for Oral Solution (NCT06721871)
- 2024-10-23Results posted on the registry: Vertex Pharmaceuticals Incorporated, IVA (NCT03277196)
- 2024-09-19Results posted on the registry: Vertex Pharmaceuticals Incorporated, LUM/IVA (NCT04235140)
- 2024-08-01Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT05274269)
- 2024-06-20Also stopped (terminated): Novartis Pharmaceuticals, QBW251 + Placebo (NCT04268823)
- 2024-06-14Phase 3 first posted: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT06460506)
- 2024-06-13Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-121/TEZ/D-IVA + ELX/TEZ/IVA (NCT05076149)
- 2024-06-10Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-121/TEZ/D-IVA + ELX/TEZ/IVA (NCT05033080)
- 2024-05-08Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT03525574)
- 2024-05-08Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04545515)
- 2024-01-16Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04058366)
- 2023-12-21Results posted on the registry: University of Alabama at Birmingham, Ivacaftor 150 MG + Placebo (NCT03085485)
- 2023-12-11Also stopped (withdrawn): Universidad Europea de Madrid, CFTR Modulators (NCT04415268)
- 2023-11-18Results posted on the registry: University of California, San Francisco, Neratinib + Trastuzumab (NCT03094052)
- 2023-10-04Results posted on the registry: Novartis Pharmaceuticals, QBW251 + Placebo (NCT04268823)
- 2023-10-03Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04969224)
- 2023-09-07Results posted on the registry: Vertex Pharmaceuticals Incorporated, IVA (NCT02725567)
- 2023-08-03Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04599465)
- 2023-07-28Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04362761)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision