Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 16:19 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Panobinostat in Combination With Daratumumab, Bortezomib and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma
NCT04956302 · Abdullah Khan · PHASE1 · terminated · last registry update 2024-06-06 · Multiple myeloma · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “PI Decision” | Open Targets' class: business administrative | Registry record, Abdullah Khan |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CD38 in multiple myeloma within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-06-04Results posted on the registry: Mayo Clinic, Daratumumab + Dexamethasone (NCT03012880)
- 2025-05-20Results posted on the registry: Janssen Research & Development, LLC, Cilta-cel + Pomalidomide (NCT04181827)
- 2025-05-18Also stopped (terminated): Mayo Clinic, Belantamab Mafodotin + Daratumumab (NCT04892264)
- 2025-05-09Results posted on the registry: GlaxoSmithKline, Belantamab mafodotin + Daratumumab (NCT06868667)
- 2025-05-02Results posted on the registry: Gilead Sciences, Magrolimab + Daratumumab (NCT04892446)
- 2025-05-02Also stopped (terminated): Gilead Sciences, Magrolimab + Daratumumab (NCT04892446)
- 2025-05-01Phase 3 first posted: Celltrion, CT-P44(Daratumumab) + Darzalex Faspro(Daratumumab) (NCT06952478)
- 2025-04-23Results posted on the registry: GlaxoSmithKline, Belantamab mafodotin + Daratumumab (NCT06868654)
- 2025-04-20Results posted on the registry: Janssen Research & Development, LLC, Daratumumab + Lenalidomide (NCT03901963)
- 2025-04-17Phase 3 first posted: European Myeloma Network B.V., Linvoseltamab + Daratumumab (NCT06932562)
- 2025-04-13Results posted on the registry: Intergroupe Francophone du Myelome, Bortezomib (VELCADE), Thalidomide, and Dexamethasone (VTD) + Bortezomib, Thalidomide, Dexamethasone (VTD) + daratumumab (NCT02541383)
- 2025-04-09Phase 3 first posted: Intergroupe Francophone du Myelome, Elranatamab + Lenalidomide (Revlimid®) (NCT06918002)
- 2025-03-30Also stopped (terminated): Janssen Research & Development, LLC, Carfilzomib 20 mg/m^2 + Carfilzomib 70 mg/m^2 (NCT03871829)
- 2025-03-26Phase 3 first posted: Shanghai Henlius Biotech, HLX15-IV + Darzalex (NCT06895512)
- 2025-03-11Phase 3 first posted: GlaxoSmithKline, Belantamab mafodotin + Daratumumab (NCT06868667)
- 2025-03-11Phase 3 first posted: GlaxoSmithKline, Belantamab mafodotin + Daratumumab (NCT06868654)
- 2025-02-25Results posted on the registry: Hackensack Meridian Health, Daratumumab + Pomalidomide (NCT04700176)
- 2025-02-25Also stopped (terminated): Hackensack Meridian Health, Daratumumab + Pomalidomide (NCT04700176)
- 2024-12-30Results posted on the registry: H. Lee Moffitt Cancer Center and Research Institute, Daratumumab Injection + Dexamethasone Oral (NCT04151667)
- 2024-12-24Results posted on the registry: Stichting European Myeloma Network, Daratumumab + Velcade (NCT03710603)
- 2024-12-19Phase 3 first posted: Qilu Pharmaceutical Co., Ltd., QL2109 + Pomalidomide (NCT06742138)
- 2024-11-07Phase 3 first posted: GlaxoSmithKline, Belantamab mafodotin + Lenalidomide (NCT06679101)
- 2024-10-24Results posted on the registry: GlaxoSmithKline, Belantamab mafodotin + Daratumumab (NCT04246047)
- 2024-10-02Results posted on the registry: Takeda, TAK-981 + Mezagitamab (NCT04776018)
- 2024-10-02Also stopped (terminated): Takeda, TAK-981 + Mezagitamab (NCT04776018)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision