Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:50 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Study of Roxadustat for Reducing the Incidence of Acute Kidney Injury After Coronary Artery Bypass Grafting
NCT05010460 · Peking Union Medical College Hospital · PHASE2 · terminated · last registry update 2025-12-09 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “slow enrollment and inability to reach the planned sample size within the expected timeframe” | – | Registry record, Peking Union Medical College Hospital |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against EGLN2 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-08-04Also stopped (terminated): GlaxoSmithKline, GSK1278863 + Placebo (NCT02075463)
- 2026-07-23Phase 3 first posted: Kyntra Bio, Roxadustat + Placebo (NCT07722988)
- 2026-07-07Also stopped (withdrawn): Peking Union Medical College Hospital, Roxadustat in combination with retinoic acid (NCT06020833)
- 2026-05-04Phase 3 first posted: Geoff Block, Epoetin alga (Epogen)/vadadustat (NCT07565701)
- 2025-12-23Phase 3 first posted: Qilu Pharmaceutical Co., Ltd., Daprodustat + Darbepoetin alfa (NCT07300111)
- 2025-11-10Results posted on the registry: GlaxoSmithKline, Daprodustat (NCT05682326)
- 2025-10-01Also stopped (withdrawn): Akebia Therapeutics, Vadadustat (NCT05082584)
- 2025-10-01Also stopped (withdrawn): Akebia Therapeutics, vadadustat (NCT05082571)
- 2025-07-25Phase 3 first posted: Paul Potnuru, Vadadustat 900mg + Vadadustat 1200mg (NCT07086755)
- 2025-05-22Results posted on the registry: Akebia Therapeutics, Vadadustat + Darbepoetin alfa (NCT04313153)
- 2025-03-30Phase 3 first posted: Akebia Therapeutics, Erythropoiesis-Stimulating Agent (ESA) + Vadadustat (NCT06901505)
- 2025-03-26Results posted on the registry: The University of Texas Health Science Center, Houston, vadadustat + placebo (NCT04478071)
- 2025-01-15Results posted on the registry: Akebia Therapeutics, Vadadustat + Mircera® (NCT04707768)
- 2025-01-13Phase 3 first posted: Second Affiliated Hospital, Zhejiang University, School of Medicine, Roxadustat (NCT06772272)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision