Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 06:48 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy
NCT05017246 · Washington University School of Medicine · PHASE2 · terminated · last registry update 2025-07-31 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Low accrual” | – | Registry record, Washington University School of Medicine |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against SCN4A within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-06-26Also stopped (terminated): Tsai-Wei Huang, a drug against SCN4A (NCT05625854)
- 2026-05-26Results posted on the registry: Eli Lilly and Company, Orforglipron + Midazolam (NCT06704763)
- 2026-05-18Results posted on the registry: University of Alabama at Birmingham, Psilocybin + Diphenhydramine (NCT02037126)
- 2026-05-15Phase 3 first posted: Cairo University, phenytoin cream (NCT07590375)
- 2026-05-13Also stopped (terminated): Otsuka Pharmaceutical Development & Commercialization, Inc., AVP-786 + Placebo (NCT02534038)
- 2026-05-04Also stopped (terminated): Ottawa Heart Institute Research Corporation, Antiarrhythmic Drug Therapy (NCT02114528)
- 2026-04-24Results posted on the registry: National Institute on Drug Abuse (NIDA), SXC-2023 + SXC-2023 Placebo (NCT06343532)
- 2026-04-07Also stopped (suspended): University of California, Los Angeles, Psilocybin (NCT06102434)
- 2026-03-13Also stopped (withdrawn): Christopher D. Verrico, Exenatide + Placebo (NCT06252623)
- 2026-02-06Results posted on the registry: Q2i, LLC, a drug against SCN4A (NCT05180669)
- 2026-02-06Also stopped (terminated): Q2i, LLC, a drug against SCN4A (NCT05180669)
- 2025-12-23Results posted on the registry: Johns Hopkins University, Suvorexant (dual orexin receptor antagonist) + Placebo (NCT05546515)
- 2025-12-12Results posted on the registry: Eli Lilly and Company, Imlunestrant + Repaglinide (NCT05444556)
- 2025-11-14Results posted on the registry: University of North Carolina, Chapel Hill, Phenobarbital Sodium Injection + Levetiracetam (NCT06081283)
- 2025-11-14Also stopped (terminated): University of North Carolina, Chapel Hill, Phenobarbital Sodium Injection + Levetiracetam (NCT06081283)
- 2025-10-29Results posted on the registry: Otsuka Pharmaceutical Development & Commercialization, Inc., Placebo + AVP-786-28 (NCT03095066)
- 2025-10-20Also stopped (withdrawn): University of Wisconsin, Madison, a drug against SCN4A (NCT06985940)
- 2025-10-20Also stopped (withdrawn): Mclean Hospital, Lorcaserin + Placebo Oral Tablet (NCT03266939)
- 2025-10-15Results posted on the registry: Otsuka Pharmaceutical Development & Commercialization, Inc., AVP-786 (NCT02446132)
- 2025-10-15Also stopped (terminated): Otsuka Pharmaceutical Development & Commercialization, Inc., AVP-786 (NCT02446132)
- 2025-09-30Results posted on the registry: VA Office of Research and Development, a drug against SCN4A (NCT03799341)
- 2025-09-24Results posted on the registry: Medical University of South Carolina, N-acetylcysteine (NCT04155632)
- 2025-08-05Results posted on the registry: William Stoops, Cocaine + Placebo oral capsule (NCT05019430)
- 2025-07-31Phase 3 first posted: Lupin Ltd., Granular powder in unit dose foil-lined sachet Mexiletine (PR) + Oral Capsule Mexiletine (IR) (NCT07097701)
- 2025-07-29Results posted on the registry: Tempero Bio, Inc., Cohort 1 - TMP-301 + Placebo (NCT06025396)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision