Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 03:22 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Ladarixin as Adjunctive Therapy to Improve Insulin Sensitivity and Glucometabolic Outcomes in Type 1 Diabetes
NCT05035368 · Dompé Farmaceutici S.p.A · PHASE2 · withdrawn · last registry update 2023-12-22 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Dompé decided to withdraw LDX0121 following an internal re-planning and an extensive review of the study design. At the time of withdrawal, no site had been activated and the drug had not been sent to investigators. No patients had been enrolled.” | – | Registry record, Dompé Farmaceutici S.p.A |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CXCR1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2024-12-11Results posted on the registry: Dompé Farmaceutici S.p.A, Reparixin (NCT03031470)
- 2024-12-11Results posted on the registry: Dompé Farmaceutici S.p.A, Repertaxin (NCT00224406)
- 2024-06-13Results posted on the registry: Dompé Farmaceutici S.p.A, Reparixin (NCT04878055)
- 2024-04-30Also stopped (withdrawn): Dompé Farmaceutici S.p.A, Reparixin + Placebo (NCT05212701)
- 2024-03-29Also stopped (withdrawn): NYU Langone Health, Sotorasib + Ladarixin (NCT05815186)
- 2024-01-08Also stopped (terminated): Dompé Farmaceutici S.p.A, Reparixin + Standard of care (NCT04794803)
- 2023-05-03Results posted on the registry: National Cancer Institute (NCI), SX-682 + M7824 (NCT04574583)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision