Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 16:31 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Marizomib Central Nervous System (CNS)
NCT05050305 · Dana-Farber Cancer Institute · PHASE2 · withdrawn · last registry update 2024-07-16 · Multiple myeloma · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study support withdrawn” | Open Targets' class: business administrative | Registry record, Dana-Farber Cancer Institute |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PSMB2 in multiple myeloma within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-06-26Results posted on the registry: Emory University, Dexamethasone + Ixazomib (NCT02765854)
- 2025-06-04Results posted on the registry: Mayo Clinic, Daratumumab + Dexamethasone (NCT03012880)
- 2025-05-02Results posted on the registry: Gilead Sciences, Magrolimab + Daratumumab (NCT04892446)
- 2025-05-02Also stopped (terminated): Gilead Sciences, Magrolimab + Daratumumab (NCT04892446)
- 2025-03-30Also stopped (terminated): Janssen Research & Development, LLC, Carfilzomib 20 mg/m^2 + Carfilzomib 70 mg/m^2 (NCT03871829)
- 2025-03-21Results posted on the registry: Millennium Pharmaceuticals, Inc., Ixazomib (NCT03748953)
- 2025-03-17Phase 3 first posted: Peking University People's Hospital, KPD (carfilzomib, pomalidomide, and dexamethasone) consolidation (NCT06879379)
- 2025-03-12Results posted on the registry: Takeda, Ixazomib (NCT02924272)
- 2025-03-05Results posted on the registry: Dana-Farber Cancer Institute, Ixazomib + Lenalidomide (NCT02916771)
- 2025-03-04Also stopped (terminated): Roswell Park Cancer Institute, Abatacept + Dexamethasone (NCT03457142)
- 2025-02-19Also stopped (terminated): Intergroupe Francophone du Myelome, Ixazomib/Pomalidomide/Dexamethasone (NCT03683277)
- 2025-01-28Results posted on the registry: M.D. Anderson Cancer Center, Ixazomib Citrate + Lenalidomide (NCT01718743)
- 2024-11-19Also stopped (withdrawn): Kathleen Dorritie, Mezigdomide + Ixazomib (NCT06050512)
- 2024-09-26Phase 3 first posted: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company, BMS-986393 + Cyclophosphamide (NCT06615479)
- 2024-09-26Results posted on the registry: Amgen, Immediate Release (IR) Formulation + Gastro-Retentive (GR) Formulation (NCT02939183)
- 2024-09-19Results posted on the registry: Suzanne Lentzsch, MD, Bendamustine + Carfilzomib (NCT02002598)
- 2024-09-19Also stopped (terminated): Suzanne Lentzsch, MD, Bendamustine + Carfilzomib (NCT02002598)
- 2024-08-20Phase 3 first posted: Assistance Publique - Hôpitaux de Paris, Dexamethasone (NCT06561854)
- 2024-08-01Results posted on the registry: National Cancer Institute (NCI), Ixazomib Citrate + Lenalidomide (NCT03941860)
- 2024-07-26Results posted on the registry: Corewell Health West, Cohort 1: Carfilzomib 15 mg/m2 + Cohort 2: Carfilzomib 20 mg/m2 (NCT02148913)
- 2024-07-16Results posted on the registry: Wake Forest University Health Sciences, Carfilzomib, lenalidomide, dexamethasone (KRd) + Daratumumab (NCT04113018)
- 2024-06-13Results posted on the registry: Mayo Clinic, Cyclophosphamide + Daratumumab (NCT01415882)
- 2024-05-31Also stopped (withdrawn): Celgene, Alnuctamab + Pomalidomide (NCT06232707)
- 2024-05-16Results posted on the registry: Roswell Park Cancer Institute, Abatacept + Dexamethasone (NCT03457142)
- 2024-05-14Phase 3 first posted: Kite, A Gilead Company, Anitocabtagene Autoleucel + Cyclophosphamide (NCT06413498)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision