Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:26 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Study to Evaluate the Efficacy of Uproleselan in Combination With Chemotherapy in Chinese Patients With R/R AML
NCT05054543 · Apollomics Inc. · PHASE3 · terminated · last registry update 2025-06-27 · Acute myeloid leukemia · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “In light of the strategic realignment of the company's development focus, it has been determined to discontinue the further development of Uproleselan Injection.” | Open Targets' class: business administrative | Registry record, Apollomics Inc. |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against SELE in acute myeloid leukemia within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-05-05Results posted on the registry: National Cancer Institute (NCI), Cytarabine + Fludarabine (NCT05146739)
- 2026-02-23Also stopped (terminated): Brian Jonas, Azacitidine + Uproleselan (NCT04964505)
- 2026-01-21Results posted on the registry: National Cancer Institute (NCI), Cytarabine + Daunorubicin (NCT03701308)
- 2025-10-20Results posted on the registry: M.D. Anderson Cancer Center, Cladribine + Cytarabine (NCT04848974)
- 2024-08-19Also stopped (terminated): Malika Kapadia, Uproleselan + Fludarabine (NCT05569512)
- 2024-07-29Also stopped (terminated): GlycoMimetics Incorporated, Uproleselan + Placebo (NCT03616470)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision