Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 02:12 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Dual-dose Aprepitant to Reduce Postoperative Nausea and Vomiting After Laparoscopic Bariatric Surgery.
NCT05189756 · Insel Gruppe AG, University Hospital Bern · PHASE4 · terminated · last registry update 2025-02-27 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Low recruiting rate” | – | Registry record, Insel Gruppe AG, University Hospital Bern |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against TACR1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-02-17Phase 3 first posted: The Affiliated People's Hospital of Ningbo University, Fosaprepitant + Fosaprepitant (NCT07413809)
- 2026-02-12Results posted on the registry: Bayer, Elinzanetant (BAY3427080) + Placebo (NCT05099159)
- 2026-02-12Results posted on the registry: Bayer, Elinzanetant (BAY3427080) + Placebo (NCT05042362)
- 2025-12-01Results posted on the registry: Bayer, Elinzanetant (BAY3427080) + Placebo (NCT05030584)
- 2025-11-25Phase 3 first posted: Centre hospitalier de l'Université de Montréal (CHUM), Aprepitant 40mg + Placebo (NCT07248280)
- 2025-11-10Results posted on the registry: Bayer, Elinzanetant (NCT06112756)
- 2025-10-29Results posted on the registry: Bayer, Elinzanetant (BAY3427080) + Placebo (NCT05587296)
- 2025-10-29Results posted on the registry: Helsinn Healthcare SA, NEPA (300mg netupitant/0.5mg palonosetron) + Granisetron, 2 mg (oral) or 1 mg (IV) OR Palonosetron, 0.5 mg (oral), 0.25mg (IV) OR Ondansetron, 16 mg (oral) or 8 mg (IV) OR Dolasetron 100 mg (oral) OR Tropisetron 5 mg (oral or IV) (NCT04817189)
- 2025-09-25Results posted on the registry: University of Rochester NCORP Research Base, Dexamethasone + Netupitant/Palonosetron Hydrochloride (NCT03367572)
- 2025-08-15Phase 3 first posted: The First Affiliated Hospital of Xinxiang Medical College, Medroxyprogesterone acetate oral suspension + high antiemetic regimen (NCT07124195)
- 2025-07-23Phase 3 first posted: Qilu Pharmaceutical Co., Ltd., QLM2010 for injection;dexamethasone + fosaprepitant dimeglumine for injection;palonosetron hydrochloride injection;dexamethasone (NCT07081256)
- 2025-06-18Results posted on the registry: University of Michigan Rogel Cancer Center, Ondansetron + Dexamethasone (NCT04503668)
- 2025-06-18Also stopped (terminated): University of Michigan Rogel Cancer Center, Ondansetron + Dexamethasone (NCT04503668)
- 2025-05-09Results posted on the registry: Vanda Pharmaceuticals, Tradipitant + Placebo (NCT03772340)
- 2025-05-04Results posted on the registry: Helsinn Healthcare SA, Fosnetupitant 235 mg solution + Akynzeo solution (NCT06840769)
- 2025-05-04Also stopped (terminated): Helsinn Healthcare SA, Fosnetupitant 235 mg solution + Akynzeo solution (NCT06840769)
- 2025-05-01Phase 3 first posted: Jiuda Zhao, standard quadruple antiemetic therapy + standard quadruple antiemetic therapy (NCT06952920)
- 2025-04-17Phase 3 first posted: Qilu Pharmaceutical (Hainan) Co., Ltd., Aprepitant Injection + Aprepitant Injection Placebo (NCT06932107)
- 2025-04-04Results posted on the registry: Vanda Pharmaceuticals, Tradipitant + Placebo (NCT05903924)
- 2025-02-20Phase 3 first posted: Vanda Pharmaceuticals, Tradipitant (NCT06836557)
- 2024-12-11Results posted on the registry: Vanda Pharmaceuticals, Tradipitant + Placebo (NCT04327661)
- 2024-10-24Results posted on the registry: Georgetown University, mFOLFIRINOX (NCT03885284)
- 2024-09-19Phase 3 first posted: Augusta University, Olanzapine (NCT06588413)
- 2024-08-30Also stopped (withdrawn): University of Nebraska, aprepitant (NCT01186029)
- 2024-08-09Phase 3 first posted: CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd., Aprepitant Injection + Aprepitant Injection Placebo (NCT06543966)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision