Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 00:42 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Efficacy and Safety of Canakinumab for the Treatment of Anemia in LR-MDS Patients
NCT05237713 · University of Leipzig · PHASE2 · terminated · last registry update 2024-05-06 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Slow recruitment. It is not considered likely that the CANFIRE trial will be able to reach the target number of patients. Clinical responders will be further treated within the trial (expected duration: 3 years after stop of enrollment).” | – | Registry record, University of Leipzig |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against IL1B within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-05-06Results posted on the registry: Novartis Pharmaceuticals, Canakinumab (NCT04795466)
- 2025-04-29Also stopped (terminated): Novartis Pharmaceuticals, Canakinumab (ACZ885) + Placebo (NCT01731990)
- 2025-04-08Results posted on the registry: Pancreatic Cancer Action Network, Canakinumab injection; spartalizumab, nab-paclitaxel, gemcitabine (NCT04581343)
- 2025-03-11Results posted on the registry: Imperial College London, Canakinumab 150mg/ml solution for injection + Placebo (NCT03775109)
- 2024-10-09Also stopped (terminated): Novartis Pharmaceuticals, Canakinumab + Placebo (NCT03447769)
- 2024-10-08Results posted on the registry: Novartis Pharmaceuticals, canakinumab + canakinumab-matching placebo (NCT03631199)
- 2024-07-11Phase 3 first posted: AO GENERIUM, GNR-086 + Ilaris® (NCT06497491)
- 2024-06-21Phase 3 first posted: AbbVie, Lutikizumab + Placebo (NCT06468228)
- 2024-06-20Also stopped (terminated): Novartis Pharmaceuticals, Canakinumab + Pembrolizumab (NCT03968419)
- 2024-01-30Results posted on the registry: Novartis Pharmaceuticals, Canakinumab + Placebo (NCT03447769)
- 2024-01-18Results posted on the registry: Novartis Pharmaceuticals, PDR001 + LAG525 (NCT03484923)
- 2023-08-21Also stopped (terminated): Novartis Pharmaceuticals, Canakinumab + Docetaxel (NCT03626545)
- 2023-07-03Results posted on the registry: Novartis Pharmaceuticals, Canakinumab + Pembrolizumab (NCT03968419)
- 2023-06-22Results posted on the registry: Novartis Pharmaceuticals, Canakinumab + Docetaxel (NCT03626545)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision