Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 21:41 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Inhalational (Sevoflurane) Versus Intravenous (Propofol) Sedation in Adults With a Moderate Form of ARDS
NCT05259631 · Negovsky Reanimatology Research Institute · PHASE3 · terminated · last registry update 2026-11-10 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Financial problems” | – | Registry record, Negovsky Reanimatology Research Institute |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against GLRA1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-10-29Phase 3 first posted: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Sevoflurane + propofol (drug) (NCT07902791)
- 2026-10-23Also stopped (terminated): Ciusss de L'Est de l'Île de Montréal, Dexmedetomidine + Placebo (NCT05615194)
- 2026-10-13Phase 3 first posted: Assiut University, Lidocaine + 0.9% Normal Saline (NCT07871266)
- 2026-10-05Results posted on the registry: Ankara City Hospital Bilkent, Sevoflurane (Volatile Anesthetic) + Propofol 1% (NCT07092046)
- 2026-08-21Also stopped (withdrawn): The University of Hong Kong, Propofol + Sevoflurane (NCT04002271)
- 2026-08-14Results posted on the registry: Milton S. Hershey Medical Center, Hybrid anesthesia (propofol + sevoflurane) + Propofol only TIVA (NCT05759481)
- 2026-07-23Results posted on the registry: University of Florida, TIVA + Balanced anesthesia (NCT04281017)
- 2026-06-30Also stopped (withdrawn): Jacques E. Chelly, Opioid-free anesthesia + Opioid-based anesthesia (NCT07211399)
- 2026-03-24Results posted on the registry: Sedana Medical, Isoflurane + Propofol (NCT05312385)
- 2026-03-05Also stopped (withdrawn): The Cleveland Clinic, Desflurane + Isoflurane (NCT06252207)
- 2026-03-03Results posted on the registry: Sedana Medical, Isoflurane + Propofol (NCT05327296)
- 2026-02-25Results posted on the registry: Hospital dos Lusíadas, Opioid-Based Anesthesia (Remifentanil-Based Protocol) + Opioid-Free Anesthesia (Dexmedetomidine-Ketamine-Lidocaine Protocol) (NCT07337135)
- 2026-02-10Also stopped (terminated): University Hospital, Rouen, Prolonged sedation with isoflurane + Prolonged sedation with midazolam (NCT04710914)
- 2025-12-31Results posted on the registry: VA Pittsburgh Healthcare System, Propofol + Sevoflurane (NCT02527083)
- 2025-12-23Phase 3 first posted: Ain Shams University, Balanced anesthesia + Lidocaine spray (NCT07299630)
- 2025-12-17Phase 3 first posted: Hopital Charles Nicolle, Sevoflurane + Desflurane (NCT07289945)
- 2025-11-26Results posted on the registry: Beth Israel Deaconess Medical Center, Ropivacaine + Ketamine (NCT05279898)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision