Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 04:03 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Study to Evaluate Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of Natalizumab (BG00002) Administered Subcutaneously to Japanese Participants With Relapsing-Remitting Multiple Sclerosis
NCT05265728 · Biogen · PHASE3 · terminated · last registry update 2025-11-25 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Due to sponsor decision, not for efficacy or safety reasons.” | – | Registry record, Biogen |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against ITGA4 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-06-15Results posted on the registry: Takeda, Vedolizumab (NCT04738942)
- 2026-05-06Also stopped (terminated): Mats Remberger, Decidua Stroma Cells (DSC) + Best available Treatment (BAT) (NCT04118556)
- 2026-04-30Results posted on the registry: Takeda, Vedolizumab (NCT04779307)
- 2026-03-16Also stopped (terminated): University Hospital, Strasbourg, France, a drug against ITGA4 (NCT02904876)
- 2026-03-13Results posted on the registry: Takeda, Vedolizumab (NCT03196427)
- 2025-12-26Also stopped (terminated): Alvotech Swiss AG, AVT16 + Vedolizumab (NCT06570772)
- 2025-12-26Also stopped (withdrawn): Therakos LLC, Methoxsalen + Infliximab (NCT06646016)
- 2025-11-28Results posted on the registry: Abivax S.A., ABX464 100 mg + ABX464 50 mg (NCT03760003)
- 2025-09-17Results posted on the registry: Washington University School of Medicine, Vedolizumab 300 MG Injection [Entyvio] (NCT03142321)
- 2025-04-03Results posted on the registry: Takeda, Vedolizumab SC (NCT02620046)
- 2025-04-02Results posted on the registry: University of Wisconsin, Madison, Shingrix (NCT03798691)
- 2025-03-18Phase 3 first posted: AbbVie, Risankizumab + Risankizumab (NCT06880744)
- 2025-02-12Results posted on the registry: Takeda, Vedolizumab IV (NCT04804540)
- 2025-01-22Results posted on the registry: State University of New York at Buffalo, Natalizumab (NCT03046251)
- 2025-01-15Also stopped (withdrawn): Case Comprehensive Cancer Center, Natalizumab (NCT03811886)
- 2025-01-01Phase 3 first posted: Federal Research Institute of Pediatric Hematology, Oncology and Immunology, Conditioning regimen: Treosulfan 42 g/m2/course or total body irradiation 12 Gray/course, Etoposide 60 mg/kg , Fludarabine 150 (NCT06756152)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision