Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 20:03 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Study of Novel Regimens in Relapsed or Refractory Multiple Myeloma
NCT05289492 · iTeos Therapeutics · PHASE1 · terminated · last registry update 2024-10-26 · Multiple myeloma · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Company operational decision. Decision to stop study is not due to safety or efficacy concerns” | Open Targets' class: business administrative | Registry record, iTeos Therapeutics |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CRBN in multiple myeloma within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-10-21Also stopped (terminated): University of California, San Diego, Ixazomib + Pomalidomide (NCT03590652)
- 2025-10-08Also stopped (terminated): Amgen, AMG 701 + Pomalidomide (NCT03287908)
- 2025-08-22Phase 3 first posted: Qilu Pharmaceutical Co., Ltd., QLS32015 + Pomalidomide (NCT07138209)
- 2025-08-20Results posted on the registry: Mayo Clinic, Dexamethasone + Lenalidomide (NCT05288062)
- 2025-08-06Results posted on the registry: Teva Branded Pharmaceutical Products R&D LLC, Modakafusp alfa + Lenalidomide (NCT05556616)
- 2025-06-24Results posted on the registry: Mayo Clinic, Dexamethasone + Elotuzumab (NCT03713294)
- 2025-06-11Results posted on the registry: GlaxoSmithKline, Belantamab mafodotin + Pomalidomide (NCT06956170)
- 2025-05-20Results posted on the registry: Janssen Research & Development, LLC, Cilta-cel + Pomalidomide (NCT04181827)
- 2025-05-04Phase 3 first posted: GlaxoSmithKline, Belantamab mafodotin + Pomalidomide (NCT06956170)
- 2025-05-02Results posted on the registry: Gilead Sciences, Magrolimab + Daratumumab (NCT04892446)
- 2025-05-02Also stopped (terminated): Gilead Sciences, Magrolimab + Daratumumab (NCT04892446)
- 2025-04-10Results posted on the registry: GlaxoSmithKline, Belantamab mafodotin + Bortezomib (NCT03828292)
- 2025-03-18Results posted on the registry: GlaxoSmithKline, Belantamab mafodotin + Pomalidomide (NCT04484623)
- 2025-03-18Results posted on the registry: Pfizer, PF-06863135 monotherapy IV or SC + PF-06863135 + dexamethasone (NCT03269136)
- 2025-03-17Phase 3 first posted: Peking University People's Hospital, KPD (carfilzomib, pomalidomide, and dexamethasone) consolidation (NCT06879379)
- 2025-03-04Results posted on the registry: Celgene, ACY-1215 (Ricolinostat) in combination with pomalidomide and dexamethasone (NCT01997840)
- 2025-03-04Also stopped (terminated): Celgene, ACY-1215 (Ricolinostat) in combination with pomalidomide and dexamethasone (NCT01997840)
- 2025-02-25Results posted on the registry: Hackensack Meridian Health, Daratumumab + Pomalidomide (NCT04700176)
- 2025-02-25Also stopped (terminated): Hackensack Meridian Health, Daratumumab + Pomalidomide (NCT04700176)
- 2025-02-19Also stopped (terminated): Intergroupe Francophone du Myelome, Ixazomib/Pomalidomide/Dexamethasone (NCT03683277)
- 2025-02-14Also stopped (terminated): Multiple Myeloma Research Consortium, Elotuzumab, pomalidomide, dexamethasone + Anti-LAG-3 (NCT04150965)
- 2024-12-24Results posted on the registry: Seagen Inc., SEA-BCMA + dexamethasone (NCT03582033)
- 2024-12-24Also stopped (terminated): Seagen Inc., SEA-BCMA + dexamethasone (NCT03582033)
- 2024-12-19Phase 3 first posted: Qilu Pharmaceutical Co., Ltd., QL2109 + Pomalidomide (NCT06742138)
- 2024-09-26Phase 3 first posted: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company, BMS-986393 + Cyclophosphamide (NCT06615479)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision