Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 19:11 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Trial to Evaluate Safety and Efficacy of GM-CSF /Sargramostim in Down Syndrome
NCT05482334 · University of Colorado, Denver · PHASE2 · withdrawn · last registry update 2025-04-02 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Difficulties enrolling participants due to study design” | – | Registry record, University of Colorado, Denver |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CSF2RA within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-01-21Results posted on the registry: Children's Oncology Group, Dinutuximab + Eflornithine Hydrochloride (NCT03794349)
- 2025-10-29Also stopped (terminated): University of Florida, TTRNA-DC vaccines with GM-CSF + TTRNA-xALT (NCT03396575)
- 2025-08-07Results posted on the registry: Savara Inc., Molgramostim + Placebo (NCT04544293)
- 2025-08-07Also stopped (withdrawn): Mayo Clinic, Aerosol Sargramostim + Nivolumab (NCT05717140)
- 2025-08-06Results posted on the registry: Eli Lilly and Company, Abemaciclib + Irinotecan (NCT04238819)
- 2025-08-06Also stopped (terminated): University of Florida, Autologous DCs derived from PBMC loaded with RNA encoding the human CMV matrix protein pp65-flLAMP plus GM-CSF (NCT04963413)
- 2025-04-16Results posted on the registry: New Approaches to Neuroblastoma Therapy Consortium, Dinutuximab + Vorinostat (NCT03332667)
- 2025-04-01Also stopped (terminated): Emory University, G-CSF, GM-CSF administered at extremities + G-CSF and GMCSF administered at abdomen (NCT00646763)
- 2025-01-22Results posted on the registry: Kiniksa Pharmaceuticals International, plc, mavrilimumab (NCT04447469)
- 2025-01-14Results posted on the registry: Ultimovacs ASA, UV1 + Sargramostim (NCT04382664)
- 2025-01-14Results posted on the registry: University of Florida, pp65-shLAMP DC with GM-CSF + unpulsed PBMC and saline (NCT02465268)
- 2024-12-09Results posted on the registry: Kristin Hudock, Mavrilimumab + Placebo (NCT04492514)
- 2024-11-19Results posted on the registry: Sellas Life Sciences Group, galinpepimut-S + pembrolizumab (NCT03761914)
- 2024-11-19Results posted on the registry: Sellas Life Sciences Group, Galinpepimut-S + GM-CSF (NCT01266083)
- 2024-10-09Results posted on the registry: Sellas Life Sciences Group, Galinpepimut-S + Montanide + GM-CSF + Montanide + GM-CSF (NCT01265433)
- 2024-10-08Results posted on the registry: Dendreon, sipuleucel-T (NCT03686683)
- 2024-09-19Results posted on the registry: National Cancer Institute (NCI), Cediranib + Sunitinib (NCT01391962)
- 2024-09-19Results posted on the registry: University of Washington, pUMVC3-IGFBP2-HER2-IGF1R Plasmid DNA Vaccine + Sargramostim (NCT02780401)
- 2024-09-19Results posted on the registry: Sellas Life Sciences Group, Galinpepimut-S + GM-CSF (NCT01827137)
- 2024-08-28Results posted on the registry: David Peereboom, Pembrolizumab + SurVaxM (NCT04013672)
- 2024-08-21Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Paclitaxel (NCT03498716)
- 2024-08-21Also stopped (terminated): Hoffmann-La Roche, Atezolizumab + Paclitaxel (NCT03498716)
- 2024-08-14Results posted on the registry: Children's Oncology Group, Dinutuximab + Irinotecan (NCT04385277)
- 2024-07-19Results posted on the registry: Nobelpharma, Sargramostim + Placebo (NCT04642950)
- 2024-07-03Results posted on the registry: Savara Inc., Molgramostim (NCT03482752)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision