Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Oral AMXT 1501 Dicaprate in Combination With IV DFMO
NCT05500508 · Aminex Therapeutics, Inc. · PHASE1/PHASE2 · terminated · last registry update 2024-12-24 · Diffuse midline glioma (DIPG) · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Required re-formulation of DFMO from IV to capsule to maintain safety” | Open Targets' class: study design | Registry record, Aminex Therapeutics, Inc. |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against ODC1 in diffuse midline glioma (dipg) within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
No results, stops or Phase 3 starts on the same target in that window.
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision