Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 05:01 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Sacituzumab Govitecan Before Radical Cystectomy for the Treatment of Non-Urothelial Muscle Invasive Bladder Cancer
NCT05581589 · University of Washington · PHASE2 · terminated · last registry update 2026-04-27 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study closed to accrual before meeting accrual goal due to major enrollment challenges based on the very rare disease indication studied and rapid changes in the therapy landscape.” | – | Registry record, University of Washington |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against TACSTD2 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-09-01Results posted on the registry: EMD Serono Research & Development Institute, Inc., Avelumab + Sacituzumab Govitecan (SG) (NCT05327530)
- 2026-08-03Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Enfortumab Vedotin (NCT03869190)
- 2026-08-03Also stopped (terminated): Hoffmann-La Roche, Atezolizumab + Enfortumab Vedotin (NCT03869190)
- 2026-07-22Phase 3 first posted: AstraZeneca, Dato-DXd + Rilvegostomig (NCT07720284)
- 2026-07-17Also stopped (terminated): Gilead Sciences, zamzetoclax + Docetaxel (NCT05006794)
- 2026-06-09Also stopped (terminated): Regeneron Pharmaceuticals, vidutolimod + cemiplimab (NCT04916002)
- 2026-06-02Results posted on the registry: Gilead Sciences, Sacituzumab Govitecan-hziy + Paclitaxel (NCT04527991)
- 2026-05-12Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Cobimetinib (NCT03337698)
- 2026-05-12Also stopped (terminated): Hoffmann-La Roche, Atezolizumab + Cobimetinib (NCT03337698)
- 2026-05-01Also stopped (withdrawn): MedSIR, Zimberelimab (AB122) + Domvanalimab (DOM) (NCT07134556)
- 2026-04-28Also stopped (withdrawn): National Cancer Institute (NCI), Tarlatamab + Sacituzumab Govitecan (NCT07328490)
- 2026-04-16Phase 3 first posted: Jiangsu Alphamab Biopharmaceuticals Co., Ltd, JSKN016 Injection + Eribulin Mcsilate Injection (NCT07533123)
- 2026-03-10Phase 3 first posted: MediLink Therapeutics (Suzhou) Co., Ltd., YL202 + Eribulin (NCT07461454)
- 2026-02-04Results posted on the registry: AstraZeneca, Dato-DXd + Capecitabine (NCT05104866)
- 2026-02-02Results posted on the registry: AstraZeneca, Durvalumab + Capivasertib (NCT03742102)
- 2026-01-30Results posted on the registry: Gilead Sciences, Sacituzumab Govitecan-hziy (NCT03964727)
- 2026-01-28Phase 3 first posted: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Chemotherapy/ADC Regimen + Fluorizoparib (NCT07371910)
- 2026-01-21Results posted on the registry: National Cancer Institute (NCI), Sacituzumab Govitecan + Loperamide (NCT06865677)
- 2026-01-21Also stopped (terminated): National Cancer Institute (NCI), Sacituzumab Govitecan + Loperamide (NCT06865677)
- 2025-12-18Phase 3 first posted: AstraZeneca, Datopotamab deruxtecan (Dato-DXd) + Docetaxel (NCT07291037)
- 2025-12-05Results posted on the registry: Regeneron Pharmaceuticals, vidutolimod + cemiplimab (NCT04916002)
- 2025-11-04Also stopped (terminated): Gilead Sciences, Magrolimab + Nab-Paclitaxel (NCT04958785)
- 2025-10-03Results posted on the registry: Gilead Sciences, Magrolimab + Nab-Paclitaxel (NCT04958785)
- 2025-09-30Results posted on the registry: Gilead Sciences, Sacituzumab Govitecan-hiy (NCT04319198)
- 2025-09-17Phase 3 first posted: Women's Cancer Study Group GmbH, Sacituzumab govitecan + Pembrolizumab 25 mg/1 ML Intravenous Solution [KEYTRUDA] (NCT07178730)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision