Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 02:13 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Safety and Suitability of Supplementing Early MIP Surgery (MIPS) of ICH With Pioglitazone
NCT05582707 · University of Maryland, Baltimore · PHASE2 · terminated · last registry update 2026-04-28 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Loss of Financial Sponsor” | – | Registry record, University of Maryland, Baltimore |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PPARG within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-09-18Also stopped (terminated): Gilead Sciences, MBX-102 + Placebo (NCT00814372)
- 2026-09-09Results posted on the registry: Inventiva Pharma, Lanifibranor + Placebo (NCT05232071)
- 2026-08-31Results posted on the registry: University of Texas Southwestern Medical Center, Pioglitazone 45 mg (NCT04370093)
- 2026-08-31Results posted on the registry: Emory University, Oral Anti-diabetes Drugs alone + Basal bolus insulin (NCT04416269)
- 2026-08-31Also stopped (terminated): Emory University, Oral Anti-diabetes Drugs alone + Basal bolus insulin (NCT04416269)
- 2026-07-27Results posted on the registry: The University of Texas at Arlington, Pioglitazone (NCT03471117)
- 2026-07-27Also stopped (terminated): The University of Texas at Arlington, Pioglitazone (NCT03471117)
- 2026-07-16Results posted on the registry: Intercept Pharmaceuticals, Bezafibrate 100 mg + Bezafibrate 200 mg (NCT05239468)
- 2026-07-16Results posted on the registry: Intercept Pharmaceuticals, Obeticholic acid + Bezafibrate 200 MG (NCT04594694)
- 2026-07-16Also stopped (terminated): Intercept Pharmaceuticals, Obeticholic acid + Bezafibrate 200 MG (NCT04594694)
- 2026-06-09Phase 3 first posted: Sun Yat-sen University, Group A (triple combination intensive therapy group) + Group B (standard therapy group) (NCT07635953)
- 2026-06-08Results posted on the registry: Intercept Pharmaceuticals, FDC tablet (OCA 5 mg + BZF 400 mg SR) (NCT06488911)
- 2026-06-08Also stopped (terminated): Intercept Pharmaceuticals, FDC tablet (OCA 5 mg + BZF 400 mg SR) (NCT06488911)
- 2026-03-19Results posted on the registry: United States Army Research Institute of Environmental Medicine, Pioglitazone 15mg (NCT06164665)
- 2026-02-20Phase 3 first posted: Zydus Therapeutics Inc., Saroglitazar Magnesium 1 mg + Placebo (NCT07424677)
- 2025-12-18Results posted on the registry: Zydus Therapeutics Inc., Saroglitazar Magnesium 4 mg Tablet + Placebo (NCT03617263)
- 2025-12-18Also stopped (terminated): Zydus Therapeutics Inc., Saroglitazar Magnesium 4 mg Tablet + Placebo (NCT03617263)
- 2025-10-14Phase 3 first posted: Zydus Therapeutics Inc., Saroglitazar magnesium 1 mg + Placebo (NCT07216235)
- 2025-09-02Also stopped (terminated): Zydus Therapeutics Inc., Saroglitazar Magnesium 4 mg + Placebo (NCT05211284)
- 2025-08-27Results posted on the registry: The University of Texas Health Science Center, Houston, Pioglitazone + Placebo (NCT05107765)
- 2025-08-12Also stopped (withdrawn): AbbVie, Mesalamine + Placebo (NCT05316220)
- 2025-07-16Results posted on the registry: Zydus Therapeutics Inc., Saroglitazar Magnesium 4 mg + Placebo (NCT05211284)
- 2025-07-09Phase 3 first posted: The University of Texas Health Science Center at San Antonio, Dapagliflozin 10mg Tab + Pioglitazone 15 MG and 30mg (NCT07056699)
- 2025-06-13Results posted on the registry: VA Office of Research and Development, a drug against PPARG (NCT03864146)
- 2025-06-11Also stopped (terminated): Biogen, Bardoxolone methyl (NCT03068130)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision