Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:55 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Window of Opportunity Study of Patritumab Deruxtecan in Patients With Brain Metastases
NCT05620914 · Mustafa Khasraw, MBChB, MD, FRCP, FRACP · PHASE2 · withdrawn · last registry update 2025-06-15 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study sponsor, Daiichi, decided to close for mult reasons, including drug near expiration, lack of enrollment, and their priority changes.” | – | Registry record, Mustafa Khasraw, MBChB, MD, FRCP, FRACP |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against ERBB3 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-06-12Results posted on the registry: Spectrum Pharmaceuticals, Inc, Poziotinib (NCT03318939)
- 2026-06-12Also stopped (terminated): Spectrum Pharmaceuticals, Inc, Poziotinib (NCT03318939)
- 2026-05-07Results posted on the registry: SCRI Development Innovations, LLC, U3-1402 (NCT04699630)
- 2026-04-27Also stopped (terminated): Partner Therapeutics, Inc., Afatinib Oral Tablet + Enzalutamide Pill (NCT05588609)
- 2026-02-20Also stopped (terminated): M.D. Anderson Cancer Center, Poziotinib (NCT03066206)
- 2025-12-16Results posted on the registry: Medical University of South Carolina, Sotorasib and Tarloxotinib + Sotorasib and Tarloxotinib (NCT05313009)
- 2025-12-16Also stopped (terminated): Medical University of South Carolina, Sotorasib and Tarloxotinib + Sotorasib and Tarloxotinib (NCT05313009)
- 2025-07-11Phase 3 first posted: Merck Sharp & Dohme LLC, Patritumab deruxtecan + Paclitaxel (NCT07060807)
- 2025-05-18Results posted on the registry: Daiichi Sankyo, Patritumab Deruxtecan (NCT04479436)
- 2025-05-18Also stopped (terminated): Daiichi Sankyo, Patritumab Deruxtecan (NCT04479436)
- 2025-04-03Results posted on the registry: Elevation Oncology, Seribantumab (NCT04383210)
- 2025-04-03Also stopped (terminated): Elevation Oncology, Seribantumab (NCT04383210)
- 2024-08-13Results posted on the registry: Daiichi Sankyo Co., Ltd., Patritumab Deruxtecan (NCT02980341)
- 2024-06-25Results posted on the registry: Spectrum Pharmaceuticals, Inc, Poziotinib Once Daily Dosing + Poziotinib Twice Daily Dosing (NCT04402008)
- 2024-06-25Also stopped (terminated): Spectrum Pharmaceuticals, Inc, Poziotinib Once Daily Dosing + Poziotinib Twice Daily Dosing (NCT04402008)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision