Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 21:40 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Fixed-dose Combination of Etoricoxib + Cyclobenzaprine for Pain Relief After Third Molar Extraction in Brazil
NCT05683574 · Eurofarma Laboratorios S.A. · PHASE3 · withdrawn · last registry update 2024-02-28 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Change in study strategy.” | – | Registry record, Eurofarma Laboratorios S.A. |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against HTR2A within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-02-25Results posted on the registry: Tonix Pharmaceuticals, Inc., TNX-102 SL Tablet, 2.8 mg + Placebo SL Tablet (NCT02829814)
- 2025-02-25Also stopped (terminated): Tonix Pharmaceuticals, Inc., TNX-102 SL Tablet, 2.8 mg + Placebo SL Tablet (NCT02829814)
- 2025-02-20Results posted on the registry: Albany Medical College, Ketamine (NCT02651324)
- 2025-02-07Results posted on the registry: Tonix Pharmaceuticals, Inc., TNX-102 SL Tablet, 2.8mg + Placebo SL Tablet (NCT02436096)
- 2025-02-06Results posted on the registry: Tonix Pharmaceuticals, Inc., TNX-102 SL (NCT03110575)
- 2025-02-06Also stopped (terminated): Tonix Pharmaceuticals, Inc., TNX-102 SL (NCT03110575)
- 2025-02-06Results posted on the registry: Tonix Pharmaceuticals, Inc., TNX-102 SL (NCT02421679)
- 2025-02-06Results posted on the registry: Tonix Pharmaceuticals, Inc., TNX-102 SL + Placebo SL Tablets (NCT03841773)
- 2025-02-06Also stopped (terminated): Tonix Pharmaceuticals, Inc., TNX-102 SL + Placebo SL Tablets (NCT03841773)
- 2025-02-05Results posted on the registry: Tonix Pharmaceuticals, Inc., TNX-102 SL 5.6 mg (NCT03508700)
- 2025-01-14Results posted on the registry: ACADIA Pharmaceuticals Inc., Pimavanserin (NCT04292223)
- 2024-12-31Results posted on the registry: ACADIA Pharmaceuticals Inc., Pimavanserin + Placebo (NCT03575052)
- 2024-12-20Results posted on the registry: Tonix Pharmaceuticals, Inc., TNX-102 SL Tablet, 5.6 mg + Placebo SL Tablet (NCT05273749)
- 2024-12-20Results posted on the registry: ACADIA Pharmaceuticals Inc., Pimavanserin (NCT03623321)
- 2024-12-20Also stopped (withdrawn): State University of New York - Downstate Medical Center, Pimavanserin (NCT05796167)
- 2024-12-13Results posted on the registry: Vanda Pharmaceuticals, Iloperidone + Ziprasidone (NCT00254202)
- 2024-12-11Results posted on the registry: Tonix Pharmaceuticals, Inc., TNX-102 SL Tablet 2.8 mg (NCT02589275)
- 2024-12-09Also stopped (withdrawn): Bjorn H. Ebdrup, Pimavanserin 34 milligrams (MG) [Nuplazid] (NCT03994965)
- 2024-11-27Also stopped (terminated): State University of New York - Upstate Medical University, cyclobenzaprine ER (AMRIX) + placebo (NCT01041495)
- 2024-11-20Results posted on the registry: Christine Oryhan, Opioid Anesthetics + Non Opioid Analgesics (NCT04081545)
- 2024-07-10Also stopped (withdrawn): Centre Hospitalier St Anne, CHLORPROMAZINE (CPZ) + Standard of Care (SOC) (NCT04366739)
- 2024-07-01Phase 3 first posted: Louisiana State University Health Sciences Center Shreveport, Lumateperone 42 mg + Risperidone 2 mg (NCT06482554)
- 2024-05-28Also stopped (terminated): Assistance Publique - Hôpitaux de Paris, Intranasal midazolam + Intramuscular loxapine (NCT05324852)
- 2024-05-22Results posted on the registry: Tonix Pharmaceuticals, Inc., TNX-102 SL + Placebo SL Tablet (NCT03062540)
- 2024-05-22Also stopped (terminated): Tonix Pharmaceuticals, Inc., TNX-102 SL + Placebo SL Tablet (NCT03062540)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision