Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 00:40 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Efficacy and Safety of Perampanel in the Treatment of Refractory Status Epilepticus
NCT05684978 · Wayne State University · PHASE4 · terminated · last registry update 2025-10-14 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study was not initiated.” | – | Registry record, Wayne State University |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against GRIA4 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-08-24Results posted on the registry: University of Minnesota, Topiramate Tablets (NCT04986631)
- 2026-07-02Results posted on the registry: AbbVie, Atogepant + Placebo for Atogepant (NCT05748483)
- 2026-05-22Results posted on the registry: University of Minnesota, Phentermine/Topiramate (Qsymia) + Placebo (NCT04881799)
- 2026-05-05Results posted on the registry: University of Minnesota, Phentermine Pill + Topiramate Pill (NCT04007393)
- 2026-04-16Results posted on the registry: University of California, Irvine, Nortriptyline + Topiramate + Verapamil + Paroxetine (NCT04404439)
- 2026-03-12Also stopped (terminated): University of Iowa, Metformin + Orlistat (NCT01351753)
- 2026-01-30Results posted on the registry: University of Florida, Phentermine / Topiramate Oral Product + Citrate Salts, Allopurinol, Diet (NCT04621929)
- 2026-01-22Also stopped (terminated): Supernus Pharmaceuticals, Inc., SPN-538 + Placebo (NCT04050293)
- 2026-01-14Results posted on the registry: Novo Nordisk A/S, Semaglutide + Orlistat (NCT05579249)
- 2025-12-18Also stopped (withdrawn): Eurofarma Laboratorios S.A., ADF1 Group Eurofarma drug association of Sibutramine IR 15mg / Topiramate XR 75mg + ADF2 Group Eurofarma drug association of Sibutramine IR 15mg / Topiramate XR 100mg (NCT05209984)
- 2025-11-21Results posted on the registry: Supernus Pharmaceuticals, Inc., SPN-538 + Placebo (NCT04050293)
- 2025-10-31Results posted on the registry: University of Virginia, Low-Dose Topiramate + Placebo (NCT01182766)
- 2025-09-29Phase 3 first posted: Neurocrine Biosciences, Osavampator + Placebo (NCT07196501)
- 2025-07-08Results posted on the registry: Mario Negri Institute for Pharmacological Research, Low dose carbamazepine + Standard dose carbamazepine (NCT03689114)
- 2025-05-31Also stopped (withdrawn): Janey Pratt, Topiramate + Phentermine (NCT04572217)
- 2025-05-23Results posted on the registry: University of Colorado, Denver, Phentermine + Immediate Release Topiramate (NCT04095104)
- 2025-04-11Also stopped (withdrawn): Stanford University, Topamax + Gabapentin (NCT04613024)
- 2025-02-28Also stopped (terminated): VA Office of Research and Development, a drug against GRIA4 (NCT04581603)
- 2025-02-14Also stopped (withdrawn): University of California, Los Angeles, Medical weight loss (NCT05812183)
- 2025-01-28Also stopped (suspended): University of Sao Paulo, Carbamazepine-Implant + Topiramate-Implant (NCT03307863)
- 2024-10-16Results posted on the registry: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Propranolol + Pindolol (NCT01950520)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision