Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:01 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Tiragolumab and Atezolizumab in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) and Untreated Brain Metastases
NCT05746481 · Liza Villaruz, MD · PHASE2 · terminated · last registry update 2026-01-22 · Non-small cell lung cancer · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Decision by agent provider” | Open Targets' class: business administrative | Registry record, Liza Villaruz, MD |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against TIGIT in non-small cell lung cancer within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-11-09Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT04294810)
- 2026-09-17Also stopped (terminated): Merck Sharp & Dohme LLC, Pembrolizumab/Vibostolimab + Pembrolizumab (NCT04738487)
- 2026-09-11Also stopped (terminated): Merck Sharp & Dohme LLC, Pembrolizumab/Vibostolimab + Carboplatin (NCT05226598)
- 2026-06-10Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT06267001)
- 2026-06-10Also stopped (terminated): Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT06267001)
- 2026-06-03Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT04513925)
- 2026-06-03Results posted on the registry: Hoffmann-La Roche, Tiragolumab + Atezolizumab (NCT04619797)
- 2026-05-12Results posted on the registry: BeiGene, Tislelizumab + Ociperlimab (NCT04746924)
- 2026-05-12Also stopped (terminated): BeiGene, Tislelizumab + Ociperlimab (NCT04746924)
- 2026-05-12Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Cobimetinib (NCT03337698)
- 2026-05-12Also stopped (terminated): Hoffmann-La Roche, Atezolizumab + Cobimetinib (NCT03337698)
- 2026-03-23Also stopped (withdrawn): Gustave Roussy, Cancer Campus, Grand Paris, Atezolizumab 1200 mg IV + Tiragolumab 600 mg IV (NCT06713798)
- 2026-03-11Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT04832854)
- 2026-03-11Also stopped (terminated): Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT04832854)
- 2026-02-09Results posted on the registry: BeiGene, Tislelizumab + Ociperlimab (NCT05577702)
- 2025-11-13Results posted on the registry: Merck Sharp & Dohme LLC, Pembrolizumab/Vibostolimab + Carboplatin (NCT05226598)
- 2025-10-22Results posted on the registry: Hoffmann-La Roche, Tiragolumab + Atezolizumab (NCT04256421)
- 2025-09-16Results posted on the registry: BeiGene, Ociperlimab + Tislelizumab (NCT05014815)
- 2025-08-27Results posted on the registry: SCRI Development Innovations, LLC, Atezolizumab + Standard of Care Chemotherapy (NCT03977467)
- 2025-08-26Results posted on the registry: Merck Sharp & Dohme LLC, Pembrolizumab/Vibostolimab + Pembrolizumab (NCT04738487)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision