Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:32 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors
NCT05828303 · Turning Point Therapeutics, Inc. · PHASE1 · withdrawn · last registry update 2025-04-01 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Insufficient enrollment” | – | Registry record, Turning Point Therapeutics, Inc. |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against NTRK1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-03-19Phase 3 first posted: Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd., TQB2102 Injection + Trifluridine /Tipiracil (TAS-102) tablets / Fruquintinib / Regorafenib tablets (NCT07483684)
- 2026-03-11Also stopped (withdrawn): M.D. Anderson Cancer Center, Regorafenib + Lorigerlimab (NCT07137390)
- 2026-03-09Also stopped (terminated): Translational Research in Oncology, Regorafenib in combination with pembrolizumab (NCT04777851)
- 2026-03-06Phase 3 first posted: Dompé Farmaceutici S.p.A, Cenegermin (NCT07453888)
- 2026-03-05Results posted on the registry: Wake Forest University Health Sciences, Regorafenib (NCT04327700)
- 2026-03-05Also stopped (terminated): Wake Forest University Health Sciences, Regorafenib (NCT04327700)
- 2026-02-25Also stopped (withdrawn): M.D. Anderson Cancer Center, Regorafenib + Lorigerlimab (NCT07223567)
- 2026-02-13Results posted on the registry: Dompé Farmaceutici S.p.A, rhNGF 5 μg/mL + rhNGF 10 μg/mL (NCT06244316)
- 2026-02-06Phase 3 first posted: Nanjing Sanhome Pharmaceutical, Co., Ltd., SH006 + Bevacizumab (NCT07392866)
- 2026-02-03Phase 3 first posted: Shanghai JMT-Bio Inc., JSKN003 + Physician choiced treatment, include: TAS-102, Regorafenib, Fruquintinib. (NCT07384377)
- 2026-01-30Phase 3 first posted: Ningbo Newbay Technology Development Co., Ltd, NB003 + regorafenib (NCT07379047)
- 2026-01-20Results posted on the registry: Bristol-Myers Squibb, BMS-986288 + Nivolumab (NCT03994601)
- 2026-01-20Also stopped (terminated): Anwaar Saeed, Regorafenib + Pembrolizumab (NCT06006923)
- 2026-01-05Also stopped (terminated): M.D. Anderson Cancer Center, Fulvestrant + Repotrectinib (NCT06408168)
- 2025-12-23Phase 3 first posted: Xi'an Xintong Pharmaceutical Research Co.,Ltd., Pracytarabine + regorafenib (NCT07300488)
- 2025-12-03Results posted on the registry: Bristol-Myers Squibb, Nivolumab + Trametinib (NCT03377361)
- 2025-12-02Results posted on the registry: Children's Oncology Group, Larotrectinib Sulfate (NCT03834961)
- 2025-10-16Results posted on the registry: National Cancer Institute (NCI), Larotrectinib Sulfate (NCT03213704)
- 2025-09-17Results posted on the registry: Merck Sharp & Dohme LLC, favezelimab/pembrolizumab + regorafenib (NCT05064059)
- 2025-09-17Results posted on the registry: Merck Sharp & Dohme LLC, favezelimab/pembrolizumab + regorafenib (NCT05600309)
- 2025-09-10Results posted on the registry: Memorial Sloan Kettering Cancer Center, Regorafenib (NCT02098538)
- 2025-09-04Phase 3 first posted: Nuvation Bio Inc., Taletrectinib + Placebo (NCT07154706)
- 2025-08-21Phase 3 first posted: Shanghai JMT-Bio Inc., JMT101 + Irinotecan (NCT07134205)
- 2025-07-18Results posted on the registry: Institut du Cancer de Montpellier - Val d'Aurelle, Regorafenib + Irinotecan (NCT03829462)
- 2025-05-28Phase 3 first posted: Second Affiliated Hospital, Zhejiang University, School of Medicine, Trifluridine/Tipiracil + Regorafenib + Trifluridine/tipiracil + bevacizumab (NCT06992648)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision