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Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 20:21 UTC. Every row links to its source record.

Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time

Open Label Extension of Efgartigimod in Adults With Post-COVID-19 POTS

NCT05918978 · argenx · PHASE2 · terminated · last registry update 2025-10-23 · Decision brief

No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.

What was said, and by whom

Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.

KindQuoteOur categorySource
Stated“Due to the phase 2 results of the main study (ARGX-113-2104) showing that efgartigimod-treated PC-POTS patients had no clinically meaningful improvement, the decision has been made to terminate this open-label extension study (ARGX-113-2105) study.”–Registry record, argenx

Also happening at the time. Not shown to be a cause.

Registry events on other trials of drugs against FCGRT within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.

What is not public

  • Internal portfolio and board discussions
  • Unpublished trial data and interim analyses
  • Terms of any partner or licence decision