Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 21:01 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Efficacy & Safety for LN144 With Pembrolizumab With High Risk Stage IIIb-dResectable Melanoma
NCT06190249 · James Isaacs, MD · PHASE1 · withdrawn · last registry update 2025-06-05 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Iovance withdrew support due to length of time required to meet accrual goal.” | – | Registry record, James Isaacs, MD |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against IL2RA within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-05-22Also stopped (terminated): University Hospital, Bordeaux, Interleukine-2 (NCT02389231)
- 2026-05-19Results posted on the registry: National Cancer Institute (NCI), Cyclophosphamide + Fludarabine (NCT03745326)
- 2026-05-19Also stopped (terminated): National Cancer Institute (NCI), Cyclophosphamide + Fludarabine (NCT03745326)
- 2026-05-15Also stopped (terminated): Iovance Biotherapeutics, Inc., Lifileucel + LN-145 (NCT03645928)
- 2026-05-01Results posted on the registry: Gwynn Long, M.D., ADCT-301 (NCT04639024)
- 2026-05-01Also stopped (terminated): Gwynn Long, M.D., ADCT-301 (NCT04639024)
- 2026-03-23Results posted on the registry: Novartis Pharmaceuticals, CFZ533 - Cohort 1/Cohort 2 + Mycophenolate Mofetil (MMF) (NCT03663335)
- 2026-03-16Also stopped (terminated): Radboud University Medical Center, UCB-NK cells + IL-2 (NCT04347616)
- 2026-03-09Results posted on the registry: National Cancer Institute (NCI), E7 TCR cells + Aldesleukin (NCT02858310)
- 2026-02-23Also stopped (withdrawn): Intima Bioscience, Inc., Fludarabine + Cyclophosphamide (NCT05566223)
- 2026-01-23Also stopped (terminated): National Cancer Institute (NCI), PG13-CEA_TCR (Anti-CEA TCR PBL) + Aldesleukin (NCT00923806)
- 2026-01-15Also stopped (withdrawn): Camillo Ricordi and Jay Skyler, Anti-Thymocyte Globulin (ATG) + Interleukin 2 (NCT02586831)
- 2026-01-13Results posted on the registry: Beth Israel Deaconess Medical Center, Interleukin-2 (NCT02739412)
- 2025-12-24Also stopped (withdrawn): City of Hope Medical Center, Aldesleukin + Cyclophosphamide (NCT06626256)
- 2025-12-19Results posted on the registry: National Cancer Institute (NCI), Aldesleukin + Cyclophosphamide (NCT01319565)
- 2025-12-16Results posted on the registry: Fady M Kaldas, M.D., F.A.C.S., Basiliximab 20 MG (NCT04104438)
- 2025-12-08Results posted on the registry: University of Washington, Aldesleukin + Pembrolizumab (NCT03260504)
- 2025-12-08Also stopped (terminated): University of Washington, Aldesleukin + Pembrolizumab (NCT03260504)
- 2025-12-02Results posted on the registry: National Cancer Institute (NCI), IL-2 (Aldesleukin) + Cyclophosphamide (NCT05035407)
- 2025-12-02Also stopped (terminated): National Cancer Institute (NCI), IL-2 (Aldesleukin) + Cyclophosphamide (NCT05035407)
- 2025-11-10Results posted on the registry: Alaunos Therapeutics, Neoantigen specific TCR-T cell drug product + Aldesleukin (IL-2) (NCT05194735)
- 2025-11-10Also stopped (terminated): University of Southern California, Twice-daily Tacrolimus + Once-daily envarsus XR (NCT04773392)
- 2025-09-22Also stopped (terminated): Vall d'Hebron Institute of Oncology, Cyclophosphamide + Trastuzumab (NCT05385705)
- 2025-09-11Also stopped (withdrawn): National Cancer Institute (NCI), KRAS TCR-Transduced PBL + Aldesleukin (NCT06690281)
- 2025-07-10Phase 3 first posted: Shanxi Bethune Hospital, Induction Therapy Regimen + Pre-Treatment Regimen (NCT07059156)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision