Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 16:20 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Clinical Trial to Evaluate Safety of Gusacitinib in Patients With Systemic Lupus Erythematosus (SLE) or Lupus
NCT06238531 · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · PHASE1 · withdrawn · last registry update 2025-03-13 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Drug company discontinuing study.” | – | Registry record, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against JAK3 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-02-25Also stopped (terminated): Children's Hospital Medical Center, Cincinnati, Ruxolitinib (NCT06695507)
- 2026-02-10Results posted on the registry: Memorial Sloan Kettering Cancer Center, topical ruxolitinib 1.5% cream (NCT03954236)
- 2026-02-03Results posted on the registry: National Heart, Lung, and Blood Institute (NHLBI), Ruxolitinib (NCT05998395)
- 2026-01-26Phase 3 first posted: Federal Research Institute of Pediatric Hematology, Oncology and Immunology, Cyclosporine A (CsA) + Sirolimus (NCT07366801)
- 2026-01-22Phase 3 first posted: Novartis Pharmaceuticals, Pelabresib + Ruxolitinib (NCT07357727)
- 2026-01-13Phase 3 first posted: LEO Pharma, Delgocitinib + Cream Vehicle (NCT07335588)
- 2026-01-05Phase 3 first posted: Chengdu Zenitar Biomedical Technology Co., Ltd, Flonoltinib 75mg + Ruxolitinib Phosphate (NCT07317700)
- 2025-12-22Phase 3 first posted: Bambino Gesù Hospital and Research Institute, Ruxolitinib + Blinatumomab (NCT07297914)
- 2025-12-19Results posted on the registry: Incyte Corporation, ruxolitinib cream (NCT05696392)
- 2025-12-19Also stopped (terminated): Incyte Corporation, ruxolitinib cream (NCT05696392)
- 2025-12-18Results posted on the registry: SWOG Cancer Research Network, Bosutinib + Dasatinib (NCT03654768)
- 2025-12-18Results posted on the registry: National Institute of Dental and Craniofacial Research (NIDCR), tofacitinib (NCT04496960)
- 2025-12-11Results posted on the registry: University of Colorado, Denver, Tofacitinib (NCT04246372)
- 2025-12-09Also stopped (withdrawn): Ahuva D Cices, Ritlecitinib (NCT06795373)
- 2025-11-24Results posted on the registry: Incyte Corporation, Ruxolitinib Cream + Vehicle Cream (NCT05764161)
- 2025-11-18Also stopped (withdrawn): Oncology Institute of Southern Switzerland, Ruxolitinib 20 MG (NCT03274778)
- 2025-11-14Results posted on the registry: Incyte Corporation, Ruxolitinib Cream + Vehicle Cream (NCT05755438)
- 2025-10-29Also stopped (terminated): Incyte Corporation, Ruxolitinib (NCT00726232)
- 2025-10-21Also stopped (terminated): Incyte Corporation, INCB057643 + Gemcitabine (NCT02711137)
- 2025-10-21Also stopped (terminated): Incyte Corporation, parsaclisib + ruxolitinib (NCT04551066)
- 2025-10-06Also stopped (withdrawn): Abu Dhabi Stem Cells Center, Anti-TNF + JAK inhibitor (NCT05379322)
- 2025-10-02Results posted on the registry: St. Jude Children's Research Hospital, Ruxolitinib + Mesna (NCT05579769)
- 2025-10-02Also stopped (terminated): St. Jude Children's Research Hospital, Ruxolitinib + Mesna (NCT05579769)
- 2025-10-02Also stopped (terminated): Incyte Corporation, parsaclisib + ruxolitinib (NCT04551053)
- 2025-09-16Results posted on the registry: Chang Gung Memorial Hospital, Tofacitinib (NCT06474078)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision