Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:01 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer
NCT06250036 · Royal Marsden NHS Foundation Trust · PHASE2 · suspended · last registry update 2026-08-21 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Gilead's ongoing evaluation of the wider Zimberelimab and Domvanalimab programme, following the outcomes of the STAR-221 study and the discontinuation of EDGE-Gastric studies. No safety concerns have been identified in relation to ZODIAC.” | – | Registry record, Royal Marsden NHS Foundation Trust |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against TIGIT within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-11-09Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT04294810)
- 2026-10-14Results posted on the registry: National Cancer Institute (NCI), Atezolizumab + Tiragolumab (NCT05715281)
- 2026-09-28Results posted on the registry: Merck Sharp & Dohme LLC, Pembrolizumab/Vibostolimab Co-Formulation + Pembrolizumab (NCT05007106)
- 2026-09-17Also stopped (terminated): Merck Sharp & Dohme LLC, Pembrolizumab/Vibostolimab + Pembrolizumab (NCT04738487)
- 2026-09-15Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Bevacizumab (NCT05908786)
- 2026-09-15Also stopped (terminated): Hoffmann-La Roche, Atezolizumab + Bevacizumab (NCT05908786)
- 2026-09-11Also stopped (terminated): Merck Sharp & Dohme LLC, Pembrolizumab/Vibostolimab + Carboplatin (NCT05226598)
- 2026-09-10Also stopped (terminated): Merck Sharp & Dohme LLC, Pembrolizumab/Vibostolimab + Pembrolizumab (NCT05665595)
- 2026-08-31Also stopped (terminated): Merck Sharp & Dohme LLC, Pembrolizumab + Pembrolizumab/vibostolimab coformulation (NCT02625961)
- 2026-08-27Results posted on the registry: Merck Sharp & Dohme LLC, Pembrolizumab + Vibostolimab (NCT04303169)
- 2026-08-13Results posted on the registry: Merck Sharp & Dohme LLC, Pembrolizumab + Quavonlimab (NCT04305041)
- 2026-08-03Results posted on the registry: Hoffmann-La Roche, 5-Fluorouracil (5-FU) + Leucovorin (NCT03281369)
- 2026-08-03Also stopped (terminated): Hoffmann-La Roche, 5-Fluorouracil (5-FU) + Leucovorin (NCT03281369)
- 2026-08-03Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Enfortumab Vedotin (NCT03869190)
- 2026-08-03Also stopped (terminated): Hoffmann-La Roche, Atezolizumab + Enfortumab Vedotin (NCT03869190)
- 2026-07-08Results posted on the registry: M.D. Anderson Cancer Center, Nivolumab + Etigilimab (NCT05715216)
- 2026-06-18Results posted on the registry: Hoffmann-La Roche, Tiragolumab and Atezolizumab IV FDC (NCT05661578)
- 2026-06-10Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT06267001)
- 2026-06-10Also stopped (terminated): Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT06267001)
- 2026-06-08Results posted on the registry: Merck Sharp & Dohme LLC, Pembrolizumab + Pembrolizumab/Quavonlimab (NCT04895722)
- 2026-06-04Also stopped (suspended): James Cleary, MD, PhD, ZIMBERELIMAB + DOMVANALIMAB (NCT05419479)
- 2026-06-03Results posted on the registry: Hoffmann-La Roche, Atezolizumab + Tiragolumab (NCT04513925)
- 2026-06-03Results posted on the registry: Hoffmann-La Roche, Tiragolumab + Atezolizumab (NCT04619797)
- 2026-05-12Results posted on the registry: BeiGene, Tislelizumab + Ociperlimab (NCT04746924)
- 2026-05-12Also stopped (terminated): BeiGene, Tislelizumab + Ociperlimab (NCT04746924)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision