Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 23:43 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Study of Dupilumab 300 mg Every Other Week After Endoscopic Sinus Surgery in Patients With Allergic Fungal Rhinosinusitis (AFRS) on a Background Therapy With Intranasal Corticosteroid Spray
NCT06461949 · National Institute on Deafness and Other Communication Disorders (NIDCD) · PHASE3 · withdrawn · last registry update 2024-07-25 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Closed by sponsor, lack of enrollment.” | – | Registry record, National Institute on Deafness and Other Communication Disorders (NIDCD) |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against IL4R within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-05-08Results posted on the registry: Emory University, Dupilumab + Placebo (NCT05545072)
- 2025-05-08Also stopped (terminated): Emory University, Dupilumab + Placebo (NCT05545072)
- 2025-03-19Results posted on the registry: Eli Lilly and Company, Lebrikizumab (NCT05369403)
- 2025-03-19Phase 3 first posted: Qilu Pharmaceutical Co., Ltd., QL2108 injection + Dupixent® (NCT06884891)
- 2025-03-17Results posted on the registry: Sanofi, Dupilumab SAR231893 + Inhaled Corticosteroid (NCT04456673)
- 2025-03-10Phase 3 first posted: Novartis Pharmaceuticals, Remibrutinib + Remibrutinib matching placebo (NCT06868212)
- 2025-02-14Results posted on the registry: LEO Pharma, LEO 138559 + Dupixent® (NCT05470114)
- 2025-02-14Results posted on the registry: AbbVie, Dupilumab + Upadacitinib (NCT05601882)
- 2024-12-18Results posted on the registry: Sanofi, Dupilumab SAR231893 + Placebo (NCT04678856)
- 2024-11-26Results posted on the registry: Sanofi, SAR231893 + Placebo (NCT04502862)
- 2024-11-14Phase 3 first posted: Sanofi, Dupilumab + Placebo (NCT06687967)
- 2024-11-14Phase 3 first posted: Sanofi, Dupilumab + Placebo (NCT06687980)
- 2024-10-23Results posted on the registry: University of Michigan, Dupilumab (NCT05036733)
- 2024-09-19Also stopped (terminated): Stanford University, omalizumab + dupliumab (NCT04943744)
- 2024-08-27Results posted on the registry: Regeneron Pharmaceuticals, Dupilumab + Matching Placebo (NCT04394351)
- 2024-08-21Results posted on the registry: Regeneron Pharmaceuticals, dupilumab + Placebo (NCT04442269)
- 2024-07-23Results posted on the registry: GlaxoSmithKline, GSK1070806 + Placebo (NCT04975438)
- 2024-07-10Results posted on the registry: Sanofi, Dupilumab + Placebo (NCT04400318)
- 2024-06-17Phase 3 first posted: AbbVie, Upadacitinib + Dupilumab (NCT06461897)
- 2024-05-09Also stopped (withdrawn): University of Rochester, Dupilumab (NCT06188871)
- 2024-04-29Phase 3 first posted: AbbVie, Upadacitinib 15mg Dose + Dupilumab 300mg Dose (NCT06389136)
- 2024-04-19Results posted on the registry: Tufts Medical Center, Apremilast (NCT04306965)
- 2024-04-18Results posted on the registry: Regeneron Pharmaceuticals, dupilumab + Matching placebo (NCT04203797)
- 2024-03-05Phase 3 first posted: Sanofi, Dupilumab (NCT06293053)
- 2024-02-28Results posted on the registry: Sanofi, Dupilumab SAR231893 + Inhaled Corticosteroid (NCT03930732)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision